FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * APPEL RONI   2. Issuer Name and Ticker or Trading Symbol Advaxis, Inc. [ADXS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O ADVAXIS, INC., TECHNOLOGY CENTER OF NJ, 675 US HWY ONE 3. Date of Earliest Transaction (Month/Day/Year) 10/17/2007 (Street) NORTH BRUNSWICK, NJ 08902 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 04/04/2008   J   153,846 A (1) 4,130,134 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Warrants

$ 0.4

10/17/2007

D(2)

58,581

11/12/2004

11/10/2009

Common Stock

58,581

(2)

675,897 (3)

D

Warrants

$ 0.274

10/17/2007

A(2)

85,377

11/12/2004

11/10/2009

Common Stock

85,377

(2)

675,897 (3)

D

Warrants

$ 0.4

10/17/2007

D(2)

355,528

11/12/2004

11/10/2009

Common Stock

355,528

(2)

675,897 (3)

D

Warrants

$ 0.274

10/17/2007

A(2)

518,158

11/12/2004

11/10/2009

Common Stock

518,158

(2)

675,897 (3)

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
APPEL RONI C/O ADVAXIS, INC. TECHNOLOGY CENTER OF NJ, 675 US HWY ONE NORTH BRUNSWICK, NJ 08902	X

Signatures

/s/ Roni Appel		04/14/2008
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The Reporting Person received these shares in connection with a settlement agreement regarding the termination of the Reporting Person's employment with the Issuer.
(2)	The four reported transactions involved anti-dilution adjustments of two outstanding warrants, resulting in the deemed cancellation of the "old" warrants and the deemed grant of a replacement warrant. The adjustments were necessary because the anti-dilution provision in each "old" warrant was triggered by a subsequent warrant issuance by the Issuer, resulting in a new exercise price and a change in the amount of shares underlying the warrants.
(3)	This total includes 72,362 shares of common stock issuable upon the exercise of warrants as previously reported with the Securities and Exchange Commission on July 5, 2005, but excludes options to purchase 2,379,090 common shares, as previously reported on form 4.

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