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                                  UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                             -----------------------

                                    FORM 10-Q

(Mark One)

|X|      Quarterly Report Pursuant to Section 13 or 15(d) of
         the Securities Exchange Act of 1934

         For the Quarter Ended March 31, 2007

                                       OR

|_|      Transition Report Pursuant To Section 13 Or 15(d) Of
         the Securities Exchange Act of 1934

         For the Transition Period from ___________ to _____________

                           Commission File No. 0-23047

                             -----------------------

                             SIGA Technologies, Inc.
             (Exact name of registrant as specified in its charter)

A Delaware Corporation                               IRS Employer No. 13-3864870

               420 Lexington Avenue, Suite 408, New York, NY 10170
                         Telephone Number (212) 672-9100

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days. Yes |X| No |_|.

Indicate by check mark whether the registrant is a large  accelerated  filer, an
accelerated  filer, or a  non-accelerated  filer. See definition of "accelerated
filer and large  accelerated  filer" in Rule 12b-2 of the Exchange  Act.  (Check
one):

Large Accelerated Filer |_|   Accelerated Filer |_|   Non-Accelerated Filer |X|.

Indicate by check mark whether the  registrant is a shell company (as defined in
rule 12b-2 of the Exchange Act). Yes |_| No |X|.


As of April 25,  2007 the  registrant  had  33,014,410  shares  of common  stock
outstanding.

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                             SIGA Technologies, Inc.

                                    Form 10-Q

                                Table of Contents



                                                                                                  Page No.

                                                                                                  
PART I FINANCIAL INFORMATION

Item 1. Financial Statements .....................................................................    2

Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations ....   10

Item 3. Quantitative and Qualitative Disclosure About Market Risk ................................   16

Item 4. Controls and Procedures ..................................................................   16


PART II OTHER INFORMATION

Item 1. Legal Proceedings ........................................................................   17

Item 1A. Risk Factors ............................................................................   17

Item 2. Changes in Securities, Use of Proceeds and Issuer Purchases of Equity Securities .........   17

Item 3. Defaults Upon Senior Securities ..........................................................   17

Item 4. Submission of Matters to a Vote of Security Holders ......................................   17

Item 5. Other Information ........................................................................   17

Item 6. Exhibits .................................................................................   17


SIGNATURES .......................................................................................   18



                                       1


PART I - FINANCIAL INFORMATION
Item 1 - Financial Statements

                             SIGA TECHNOLOGIES, INC.

                           CONSOLIDATED BALANCE SHEETS



                                                                              Unaudited
                                                                               March 31,     December 31,
                                                                                 2007            2006
                                                                             ------------    ------------
                                                                                       
ASSETS
Current assets
 Cash and cash equivalents ...............................................   $  9,744,739    $ 10,639,530
 Accounts receivable .....................................................      1,278,592         617,032
 Prepaid expenses ........................................................        141,590         141,032
                                                                             ------------    ------------
  Total current assets ...................................................     11,164,921      11,397,594

 Property, plant and equipment, net ......................................      1,102,627       1,320,315
 Goodwill ................................................................        898,334         898,334
 Intangible assets, net ..................................................        144,588         165,243
 Other assets ............................................................        254,228         246,201
                                                                             ------------    ------------
  Total assets ...........................................................   $ 13,564,698    $ 14,027,687
                                                                             ============    ============
LIABILITIES AND STOCKHOLDERS' EQUITY
 Current liabilities
 Accounts payable ........................................................   $  1,384,621    $  1,357,906
 Accrued expenses and other ..............................................        622,720         584,504
 Notes payable ...........................................................        107,520         107,520
                                                                             ------------    ------------
  Total current liabilities ..............................................      2,014,861       2,049,930

 Non-current portion of notes payable ....................................          1,025          22,809
 Common stock warrants ...................................................      6,132,266       4,673,098
                                                                             ------------    ------------
   Total liabilities .....................................................      8,148,152       6,745,837

 Commitments and contingencies ...........................................             --              --
 Stockholders' equity
   Common stock ($0.0001 par value, 50,000,000 shares authorized,
   32,988,010 and 32,452,210 issued and outstanding at March 31, 2007
   and December 31, 2006, respectively) ..................................          3,298           3,245
 Additional paid-in capital ..............................................     64,822,544      63,646,224
 Accumulated deficit .....................................................    (59,509,296)    (56,367,619)
                                                                             ------------    ------------
  Total stockholders' equity .............................................      5,416,546       7,281,850
                                                                             ------------    ------------
  Total liabilities and stockholders' equity .............................   $ 13,564,698    $ 14,027,687
                                                                             ============    ============



   The accompanying notes are an integral part of these financial statements.


                                       2



                             SIGA TECHNOLOGIES, INC.

                CONSOLIDATED STATEMENTS OF OPERATIONS (UNAUDITED)



                                                                        Three Months Ended
                                                                             March 31,
                                                                       2007            2006
                                                                   ------------    ------------
                                                                             
Revenues
 Research and development ......................................   $  1,867,441    $  1,394,454
                                                                   ------------    ------------

Operating expenses
 Selling, general and administrative (include $8,306 and $92,172
      of non-cash share based compensation for the three
      months ended March 31, 2007 and 2006, respectively) ......        877,116         941,540
 Research and development (include $28,643 and $29,253
      of non-cash share based compensation for the three
      months ended March 31, 2007 and 2006, respectively) ......      2,649,588       1,657,670
 Patent preparation fees .......................................        137,686         109,537
                                                                   ------------    ------------
  Total operating expenses .....................................      3,664,390       2,708,747
                                                                   ------------    ------------

  Operating loss ...............................................     (1,796,949)     (1,314,293)

Decrease in fair market value of common stock rights
 and common stock warrants .....................................     (1,459,168)     (1,525,635)
Other income, net ...............................................       114,440           6,268
                                                                   ------------    ------------
  Net loss .....................................................   $ (3,141,677)   $ (2,833,660)
                                                                   ============    ============

Weighted average shares outstanding: basic and diluted               32,590,966      26,500,648
                                                                   ============    ============
Net loss per share: basic and diluted                              $      (0.10)   $      (0.11)
                                                                   ============    ============



   The accompanying notes are an integral part of these financial statements.


                                       3


                             SIGA TECHNOLOGIES, INC.

                CONSOLIDATED STATEMENT OF CASH FLOWS (UNAUDITED)



                                                                              Three Months Ended
                                                                                   March 31,
                                                                             2007            2006
                                                                         ------------    ------------
                                                                                   
Cash flows from operating activities:
Net loss .............................................................   $ (3,141,677)   $ (2,833,660)
Adjustments to reconcile net loss to net
cash used in operating activities:
  Depreciation .......................................................        257,985          39,172
  Amortization of intangible assets ..................................         20,655         274,349
  Increase in fair market value of rights and warrants ...............      1,459,168       1,525,635
  Stock based compensation ...........................................         36,949         121,425
  Changes in assets and liabilities:
     Accounts receivable .............................................       (661,560)        624,872
     Prepaid expenses ................................................           (558)         62,266
     Other assets ....................................................         (8,027)        (10,158)
     Deferred revenue ................................................             --         917,037
     Accounts payable and accrued expenses ...........................         70,837        (681,028)
                                                                         ------------    ------------
     Net cash provided by (used in) operating activities .............     (1,966,228)         39,910
                                                                         ------------    ------------
Cash flows from investing activities:
  Capital expenditures ...............................................        (40,297)       (307,417)
                                                                         ------------    ------------
     Net cash used in investing activities ...........................        (40,297)       (307,417)
                                                                         ------------    ------------
Cash flows from financing activities:
  Proceeds from issuance of notes payable ............................             --       1,000,000
  Net proceeds from exercise of warrants and options .................      1,139,424              --
  Repayment of notes payable .........................................        (27,690)        (26,880)
                                                                         ------------    ------------
      Net cash provided by financing activities ......................      1,111,734         973,120
                                                                         ------------    ------------
Net increase (decrease) in cash and cash equivalents .................       (894,791)        705,613
Cash and cash equivalents at beginning of period .....................     10,639,530       1,772,489
                                                                         ------------    ------------
Cash and cash equivalents at end of period ...........................   $  9,744,739    $  2,478,102
                                                                         ============    ============


   The accompanying notes are an integral part of these financial statements.


                                       4


                             SIGA TECHNOLOGIES, INC.
    Notes to the March 31, 2007 Consolidated Financial Statements (Unaudited)


1. Basis of Presentation

SIGA  Technologies,  Inc.  ("SIGA" or the  "Company") is a  bio-defense  company
engaged in the discovery,  development and commercialization of products for use
in defense against  biological warfare agents such as Smallpox and Arenaviruses.
The Company is also  engaged in the  discovery  and  development  of other novel
anti-infectives,  vaccines,  and antibiotics for the prevention and treatment of
serious infectious  diseases.  The Company's anti-viral programs are designed to
prevent or limit the  replication  of viral  pathogens.  SIGA's  anti-infectives
programs target the increasingly  serious problem of drug resistant bacteria and
emerging pathogens.

The  consolidated  financial  statements  of the Company  have been  prepared in
accordance with accounting principles generally accepted in the United States of
America for interim  financial  information and the rules and regulations of the
Securities and Exchange  Commission  (the "SEC") for quarterly  reports on Forms
10-Q and should be read in conjunction with the Company's  consolidated  audited
financial  statements  and notes  thereto for the year ended  December 31, 2006,
included in the 2006 Form 10-K. All terms used but not defined  elsewhere herein
have the meaning  ascribed to them in the  Company's  2006 annual report on Form
10-K filed on March 16, 2007.  The  year-end  condensed  balance  sheet data was
derived from audited financial statements,  but does not include all disclosures
required by  accounting  principles  generally  accepted in the United States of
America. In the opinion of management, all adjustments (consisting of normal and
recurring adjustments)  considered necessary for a fair statement of the results
of the interim periods  presented have been included.  The results of operations
for the three months ended March 31, 2007 are not necessarily  indicative of the
results expected for the full year.

The accompanying consolidated financial statements have been prepared on a basis
which  assumes  that the  Company  will  continue  as a going  concern and which
contemplates  the realization of assets and the  satisfaction of liabilities and
commitments  in  the  normal  course  of  business.  The  Company  has  incurred
cumulative net losses and expects to incur additional  losses to perform further
research  and  development  activities.  The  Company  does not have  commercial
products and has limited capital  resources.  Management's  plans with regard to
these matters include  continued  development of its products as well as seeking
additional  research support funds and future financial  arrangements.  Although
management  will continue to pursue these plans,  there is no assurance that the
Company  will  be  successful  in  obtaining   sufficient  future  financing  on
commercially reasonable terms or that the Company will be able to secure funding
from  anticipated  government  contracts  and grants.  Management  believes that
existing cash balances  combined with  anticipated cash flows will be sufficient
to support  its  operations  beyond the next  twelve  months,  and will fund the
Company's business objectives during that period.

2. Significant Accounting Policies

Use of Estimates

The consolidated  financial  statements and related  disclosures are prepared in
conformity with accounting principles generally accepted in the United States of
America.  Management is required to make estimates and  assumptions  that affect
the reported  amounts of assets and  liabilities,  the  disclosure of contingent
assets and  liabilities at the date of the financial  statements and revenue and
expenses during the period reported.  These estimates include the realization of
deferred tax assets,  useful  lives and  impairment  of tangible and  intangible
assets,  and the value of options and warrants granted or issued by the Company.
Estimates and assumptions are reviewed periodically and the effects of revisions
are reflected in the financial  statements in the period they are  determined to
be necessary. Actual results could differ from these estimates.

Cash and cash equivalents

Cash and cash equivalents consist of short term, highly liquid investments, with
original  maturities of less than three months when  purchased and are stated at
cost. Interest is accrued as earned.

Property, Plant and Equipment

Property, plant and equipment are stated at cost less accumulated  depreciation.
Depreciation is provided on the  straight-line  method over the estimated useful
lives of the various asset classes.  Estimated  lives are 5 years for laboratory
equipment;  3 years for computer equipment;  7 years for furniture and fixtures;
and the life of the lease for leasehold improvements.  Maintenance,  repairs and
minor  replacements  are  charged to expense as  incurred.  Upon  retirement  or
disposal of assets,  the cost and related  accumulated  depreciation are removed
from the Balance  Sheet and any gain or loss is  reflected  in the  Statement of
Operations.


                                       5


Revenue Recognition

The Company  recognizes  revenue  from  contract  research and  development  and
research  payments in  accordance  with SEC Staff  Accounting  Bulletin No. 104,
Revenue  Recognition,  ("SAB  104").  In  accordance  with SAB 104,  revenue  is
recognized  when  persuasive  evidence of an  arrangement  exists,  delivery has
occurred,  the  fee is  fixed  or  determinable,  collectibility  is  reasonably
assured,  contractual obligations have been satisfied and title and risk of loss
have been  transferred  to the  customer.  The Company  recognizes  revenue from
non-refundable  up-front payments,  not tied to achieving a specific performance
milestone, over the period which the Company is obligated to perform services or
based on the percentage of costs incurred to date,  estimated  costs to complete
and total expected  contract  revenue.  Payments for development  activities are
recognized as revenue as earned, over the period of effort.  Substantive at-risk
milestone  payments,  which  are  based  on  achieving  a  specific  performance
milestone,  are  recognized  as revenue  when the  milestone is achieved and the
related  payment  is  due,  providing  there  is no  future  service  obligation
associated with that milestone. In situations where the Company receives payment
in advance of the  performance  of  services,  such  amounts  are  deferred  and
recognized as revenue as the related services are performed.

For the three  months  ended March 31,  2007 and 2006,  revenues  from  National
Institutes of Health ("NIH")  contracts and Small Business  Innovation  Research
("SBIR") grants were 66% and 52%, respectively,  of total revenues recognized by
the Company.

Accounts Receivable

Accounts  receivable  are recorded net of provisions for doubtful  accounts.  An
allowance  for  doubtful   accounts  is  based  on  specific   analysis  of  the
receivables.  At March 31,  2007 and  December  31,  2006,  the  Company  had no
allowance for doubtful accounts.

Research and development

Research and  development  expenses  include costs directly  attributable to the
conduct of research and development programs,  including employee related costs,
materials, supplies,  depreciation on and maintenance of research equipment, the
cost of services  provided by outside  contractors,  and facility costs, such as
rent,  utilities,  and  general  support  services.  All costs  associated  with
research  and  development  are  expensed  as  incurred.  Costs  related  to the
acquisition  of  technology  rights,  for  which  development  work is  still in
process, and that have no alternative future uses, are expensed as incurred.

Goodwill

Goodwill is recorded when the purchase price paid for an acquisition exceeds the
estimated  fair  value of the net  identified  tangible  and  intangible  assets
acquired.

The Company evaluates goodwill for impairment annually, in the fourth quarter of
each year.  In addition,  the Company  would test  goodwill  for  recoverability
between annual evaluations whenever events or changes in circumstances  indicate
that the carrying amounts may not be recoverable.  Examples of such events could
include a  significant  adverse  change in legal  matters,  liquidity  or in the
business  climate,  an adverse action or assessment by a regulator or government
organization,  loss of key personnel,  or new circumstances  that would cause an
expectation  that it is more  likely  than not that we would  sell or  otherwise
dispose of a reporting unit.  Goodwill impairment is determined using a two-step
approach in accordance with Statement of Financial  Accounting Standards No. 142
"Goodwill and Other  Intangible  Assets"  ("SFAS 142").  The  impairment  review
process  compares the fair value of the reporting unit in which goodwill resides
to its carrying  value.  In 2006,  the Company  operated as one business and one
reporting unit. Therefore, the goodwill impairment analysis was performed on the
basis of the Company as a whole using the market  capitalization  of the Company
as an estimate of its fair value.

Identified Intangible Assets

Acquisition-related intangibles at March 31, 2007, represent acquired technology
which is amortized on a straight line basis over period 2 years.

In  accordance  with  Statement  of  Financial   Accounting  Standards  No.  144
"Accounting  for the Impairment or Disposal of Long-Lived  Assets" ("SFAS 144"),
the Company performs a review of its identified  intangible  assets to determine
if facts and circumstances  exist which indicate that the useful life is shorter
than  originally  estimated  or that the  carrying  amount of assets  may not be
recoverable.  If such facts and circumstances do exist, the Company assesses the
recoverability  of  identified  intangible  assets by  comparing  the  projected
undiscounted net cash flows associated with the related asset or group of assets
over  their  remaining  lives  against  their   respective   carrying   amounts.
Impairment,  if any, is based on the excess of the carrying amount over the fair
value of those assets.  Our  estimates of projected  cash flows are dependent on
many factors, including general economic trends,  technological developments and
projected future


                                       6


contracts and government  grants. It is reasonably likely that future cash flows
associated  with our  intangible  assets may exceed or fall short of our current
projections, in which case a different amount for impairment would result.

Income taxes

Income taxes are accounted for under the asset and liability  method  prescribed
by Statement of Financial  Accounting  Standards No. 109, "Accounting for Income
Taxes."  Deferred  income taxes are recorded for temporary  differences  between
financial   statement   carrying  amounts  and  the  tax  basis  of  assets  and
liabilities.  Deferred tax assets and liabilities reflect the tax rates expected
to be in effect for the years in which the  differences are expected to reverse.
A valuation allowance is provided if it is more likely than not that some or the
entire deferred tax asset will not be realized.

Net loss per common share

The Company  computes,  presents and discloses  earnings per share in accordance
with SFAS 128 "Earnings  Per Share"  ("EPS")  which  specifies the  computation,
presentation and disclosure requirements for earnings per share of entities with
publicly held common stock or potential common stock. The statement  defines two
earnings per share calculations,  basic and diluted.  The objective of basic EPS
is to measure the performance of an entity over the reporting period by dividing
income  (loss) by the weighted  average  shares  outstanding.  The  objective of
diluted  EPS is  consistent  with  that of basic  EPS,  that is to  measure  the
performance of an entity over the reporting  period,  while giving effect to all
dilutive  potential common shares that were outstanding  during the period.  The
calculation  of diluted  EPS is similar to basic EPS except the  denominator  is
increased for the conversion of potential common shares.

The Company  incurred  losses for the three months ended March 31, 2007 and 2006
and as a result, certain equity instruments are excluded from the calculation of
diluted loss per share. At March 31, 2006, 68,038 shares of the Company's Series
A convertible preferred stock have been excluded from the computation of diluted
loss per share as they were  anti-dilutive.  These  shares were  converted  into
shares  of the  Company's  common  stock in 2006.  At  March  31,  2007 and 2006
outstanding options to purchase 7,431,412 and 8,488,727 shares, respectively, of
the Company's common stock with exercise prices ranging from $0.94 to $5.50 have
been  excluded  from the  computation  of  diluted  loss  per  share as they are
anti-dilutive.  At March 31,  2007 and 2006,  outstanding  warrants  to purchase
9,166,632 and 9,478,794,  shares,  respectively,  of the Company's common stock,
with  exercise  prices  ranging from $1.18 to $4.99 have been  excluded from the
computation of diluted loss per share as they are anti-dilutive.

Fair value of financial instruments

The carrying value of cash and cash  equivalents,  accounts  payable and accrued
expenses  approximates  fair value due to the relatively short maturity of these
instruments.  Common stock rights and warrants which are classified as assets or
liabilities  under the  provisions  of EITF  00-19,  are  recorded at their fair
market value as of each reporting period.

Concentration of credit risk

The Company has cash in bank accounts that exceed the Federal Deposit  Insurance
Corporation  insured  limits.  The Company has not experienced any losses on its
cash  accounts.  No allowance  has been  provided for  potential  credit  losses
because management believes that any such losses would be minimal.

Share-based Compensation

The  Company  accounts  for its  stock-based  compensation  programs  under  the
provisions  of  Statement  of Financial  Accounting  Standards  No. 123 (revised
2004), "Share-Based Payment" ("SFAS 123(R)"), which requires the measurement and
recognition of compensation  expense for all share-based  payment awards made to
employees  and directors  including  employee  stock options and employee  stock
purchases   related  to  the  Employee  Stock  Purchase  Plan  ("employee  stock
purchases")  based on estimated  fair  values.  The Company does not have a tock
purchase plan at the current time.

Segment information

The Company is managed  and  operated as one  business.  The entire  business is
managed by a single management team that reports to the chief executive officer.
The Company  does not operate  separate  lines of business or separate  business
entities with respect to any of its product candidates. Accordingly, the Company
does not prepare discrete financial information with respect to separate product
areas or by location and only has one reportable  segment as defined by SFAS No.
131, "Disclosures about Segments of an Enterprise and Related Information".

Recent accounting pronouncements

In  February  2007,  the FASB  issued  SFAS No. 159 "The Fair  Value  Option for
Financial  Assets  and  Financial  Liabilities"  ("FAS  159").  FAS 159  permits
entities to choose to measure  many  financial  assets and  liabilities  at fair
value. Unrealized gains and losses on items for which fair value option has been
elected are reported in earnings.


                                       7


FAS 159 is effective for fiscal years  beginning  after  November 15, 2007.  The
Company is currently  assessing the impact of FAS 159 on its financial  position
and results of operations.

Effective  January 1, 2007,  the Company  adopted  FASB  Interpretation  No. 48,
Accounting for Uncertainty in Income Taxes--an  Interpretation of FASB Statement
109 ("FIN 48"). FIN 48 prescribes a comprehensive  model for the manner in which
a company  should  recognize,  measure,  present and  disclose in its  financial
statements  all material  uncertain tax positions  that the Company has taken or
expects to take on a tax return.

Upon  adoption  of FIN  48 and  through  March  31,  2007,  the  Company  had no
unrecognized tax benefits and, therefore,  no unrecognized tax benefits that, if
recognized,  would affect the  effective  tax rate.  As of the date of adoption,
there were no tax positions  for which it is reasonably  possible that the total
amounts of  unrecognized  tax benefits will  significantly  increase or decrease
within twelve months from the date of adoption of FIN 48 or from March 31, 2007.
As of March 31, 2007, the only tax  jurisdiction to which the Company is subject
is the  United  States.  Open tax  years  relate  to years in which  unused  net
operating  losses were  generated.  Thus, upon adoption of FIN 48, the Company's
open tax years extend back to 1995. In the event that the Company concludes that
it is subject to interest and/or penalties arising from uncertain tax positions,
the Company will present  interest and penalties as a component of income taxes.
No  amounts  of  interest  or  penalties   were   recognized  in  the  Company's
Consolidated  Statements  of  Operations  or  Consolidated  Balance  Sheets upon
adoption of FIN 48 or as of and for the three months ended March 31, 2007.

3. Intangible Assets

Amortization expense recorded for the three months ended March 31, 2007 and 2006
was as follows:



                                                                   Three Months Ended
                                                                       March 31,
                                                                  2007           2006
                                                              ------------   ------------
                                                                       
Amortization of acquired grants                               $         --   $    245,337
Amortization of customer contract and grants                            --          8,357
Amortization of acquired technology                                 20,655         20,655
                                                              ------------   ------------
                                                              $     20,655   $    274,349
                                                              ------------   ------------


4. Stockholders' Equity

At  March  31,  2007,  the  Company's  authorized  share  capital  consisted  of
60,000,000  shares,  of  which  50,000,000  are  designated  common  shares  and
10,000,000 are designated  preferred shares. The Company's Board of Directors is
authorized  to issue  preferred  shares in series with  rights,  privileges  and
qualifications of each series determined by the Board.

2006 Placement

On October 19, 2006, the Company sold 2,000,000  shares of the Company's  common
stock at $4.54  per share  and  warrants  to  purchase  1,000,000  shares of the
Company's  common stock.  The warrants are exercisable at $4.99 per share at any
time and from time to time through and including the seventh  anniversary of the
closing  date.  As of March 31, 2007,  warrants to acquire  1,000,000  shares of
common stock were outstanding.

The Company  accounted for the  transaction  under the  provisions of EITF 00-19
which requires that free standing derivative financial  instruments that require
net cash  settlement be classified as assets or  liabilities  at the time of the
transaction, and recorded at their fair value. EITF 00-19 also requires that any
changes in the fair value of the derivative  instruments be reported in earnings
or  loss as long  as the  derivative  contracts  are  classified  as  assets  or
liabilities. At March 31, 2007, the fair market value of the warrants to acquire
common stock was $3.2 million.  The Company applied the  Black-Scholes  model to
calculate the fair values of the  respective  derivative  instruments  using the
contracted term of the warrants.  Management  estimates the expected  volatility
using a combination of the Company's historical volatility and the volatility of
a group of  comparable  companies.  SIGA  recorded  a loss of  $745,000  for the
increase  in the  instruments'  fair value from  December  31, 2006 to March 31,
2007.

2005 Placement

In November  2005,  the Company sold  2,000,000  shares of the Company's  common
stock at $1.00  per share  and  warrants  to  purchase  1,000,000  shares of the
Company's  common stock at an initial  exercise price of $1.18 per share, at any
time and from time to time through and including the seventh  anniversary of the
closing date. The investors were also entitled to purchase  additional shares of
the  Company's  common  stock for a gross  amount of $2.0  million at an initial
price of  $1.10  per  share  for a  period  of 90  trading  days  following  the
effectiveness  of a  registration  statement.  The rights to acquire  additional
shares  of common  stock  expired  on August  25,  2006.  As of March 31,  2007,
warrants to acquire 725,000 shares of common stock were outstanding.

The Company accounted for the transaction under the provisions of EITF 00-19. At
March 31, 2007,  the fair market  value of the warrants to acquire  common stock
was $3.0  million.  SIGA  recorded a loss of  $714,000  for the  increase in the
instruments' fair value from December 31, 2006 to March 31, 2007.


                                       8


5. Related Parties

During the three  months  ended March 31, 2007,  the Company  incurred  costs of
$12,500  related to work performed by Transtech  Pharma,  Inc., a related party,
and its affiliates.

6. Stock Compensation Plans

In January 1996, the Company  implemented  its 1996 Incentive and  Non-Qualified
Stock Option Plan (the "Plan"). The Plan as amended provides for the granting of
up to 11,000,000 shares of the Company's common stock to employees,  consultants
and outside  directors of the Company.  The exercise  period for options granted
under the Plan,  except those granted to outside  directors,  is determined by a
committee of the Board of Directors.  Stock options granted to outside directors
pursuant  to the Plan must have an  exercise  price equal to or in excess of the
fair market value of the Company's common stock at the date of grant.

For the three  months  ended  March  31,  2007 and 2006,  the  Company  recorded
compensation expense of approximately $37,000 and $121,000, respectively related
to stock options. The total fair value of options vested during the three months
ended March 31, 2007 and 2006 was 188,000 and $222,000.  The total  compensation
cost not yet  recognized  related  to  non-vested  awards at March  31,  2007 is
$832,000.  The weighted  average  period over which total  compensation  cost is
expected to be recognized is 1.56 years.

The Company did not award any option  grants during the three months ended March
31, 2007.

7. Commitments and Contingencies

As of March 31,  2007,  our  purchase  obligations  are not  material.  We lease
certain  facilities  and office space under  operating  leases.  Minimum  future
rental commitments under operating leases having  non-cancelable  lease terms in
excess of one year are as follows:



                                                      Loans and related
        Year ended December 31,   Lease obligations    interest payable    Total commitments
                                                                    
                           2007      $    576,948        $     107,521       $     684,469
                           2008           576,948               22,809             599,757
                           2009           579,648                   --             579,648
                           2010           466,448                   --             466,448
                           2011           443,748                   --             443,748
                                     ------------        -------------       -------------
        Total                        $  2,643,740        $     130,330       $   2,774,070
                                     ============        =============       =============


Other

On December 20, 2006, PharmAthene,  Inc. ("PharmAthene") filed an action against
the  Company  in the  Court of  Chancery  in the  State of  Delaware,  captioned
PharmAthene, Inc. v. SIGA Technologies, Inc., C.A. No. 2627-N. In its Complaint,
PharmAthene  asks the  Court to  order  the  Company  to  enter  into a  license
agreement  with  PharmAthene  with  respect  to  SIGA-246,  as well  as  issue a
declaration that the Company is obliged to execute such a license agreement, and
award damages  resulting from the Company's  supposed breach of that obligation.
PharmAthene  also alleges that the Company  breached an  obligation to negotiate
such a license  agreement in good faith, as well as seeks damages for promissory
estoppel  and unjust  enrichment  based on  supposed  information,  capital  and
assistance  that  PharmAthene  allegedly  provided  to the  Company  during  the
negotiation  process.  On January 9, 2007, the Company filed a motion to dismiss
the Complaint in its entirety for failure to state a claim upon which relief can
be granted.  The motion has been fully  briefed and oral  argument is  currently
scheduled  for June 1, 2007.  On January  19,  2007,  PharmAthene  served on the
Company its first request for production of documents. The Company moved to stay
discovery on January 26, 2007 and this motion was granted on March 8, 2007. SIGA
believes  that  the  claims  are  without  merit  and  plans  to  defend  itself
vigorously.


                                       9


                             SIGA TECHNOLOGIES, INC.

Item 2. Management's  Discussion and Analysis of Financial Condition and Results
        of Operations

      The following  discussion should be read in conjunction with our financial
statements  and  notes to  those  statements  and  other  financial  information
appearing  elsewhere  in  this  Quarterly  Report.  In  addition  to  historical
information,  the following  discussion and other parts of this Quarterly Report
contain forward-looking information that involves risks and uncertainties.

Overview

      Since our  inception in December  1995,  SIGA has pursued the research and
development  of novel  products  for the  prevention  and  treatment  of serious
infectious  diseases,   including  products  for  use  in  the  defense  against
biological  warfare agents such as Smallpox and  Arenaviruses.  During the third
quarter of 2006 we were awarded a 3 year,  $16.5  million  contract from the NIH
and an additional 3 year, $4.8 million SBIR Phase II continuation grant from the
NIH.  Both awards  support  the  continuing  development  of our  smallpox  drug
candidate, ST-246. Our efforts to develop ST-246 were also supported by previous
SBIR grants from the NIH totaling $5.8 million,  a $1.0 million  agreement  with
Saint Louis  University,  and a $1.6 million  contract with the U.S.  Army.  Our
initiative to advance SIGA's Arenavirus  programs is supported by a 3 year, $6.0
million SBIR grant from the NIH,  received in September  2006 and previous  SBIR
grants from the NIH totaling $6.3 million.

      Our anti-viral  programs are designed to prevent or limit the  replication
of  the  viral  pathogen.   Our  anti-infectives   programs  are  aimed  at  the
increasingly serious problem of drug resistance.  These programs are designed to
block the ability of bacteria to attach to human  tissue,  the first step in the
infection process.  We are also developing a technology for the mucosal delivery
of our vaccines  which may allow the  vaccines to activate the immune  system at
the mucus lined  surfaces of the body -- the mouth,  the nose, the lungs and the
gastrointestinal and urogenital tracts -- the sites of entry for most infectious
agents.

      We do not have  commercial  biomedical  products,  and we do not expect to
have such  products for one to three  years,  if at all. We believe that we will
need additional  funds to complete the  development of our biomedical  products.
Our plans with regard to these  matters  include  continued  development  of our
products as well as seeking  additional  research  support  funds and  financial
arrangements.  Although we continue to pursue these plans, there is no assurance
that we will be successful in obtaining  future financing on terms acceptable to
us.  Management  believes it has  sufficient  funds and projected  cash flows to
support operations beyond the next twelve months.

      Our  biotechnology  operations  are  based  in our  research  facility  in
Corvallis,  Oregon.  We continue to seek to fund a major  portion of our ongoing
antiviral,  antibiotic and vaccine  programs through a combination of government
grants,  contracts  and  strategic  alliances.  While  we have  had  success  in
obtaining strategic alliances,  contracts and grants, there is no assurance that
we will continue to be successful in obtaining  funds from these sources.  Until
additional  relationships  are  established,  we  expect  to  continue  to incur
significant  research  and  development  costs  and  costs  associated  with the
manufacturing of product for use in clinical trials and pre-clinical testing. It
is  expected  that  general  and  administrative  costs,  including  patent  and
regulatory  costs,  necessary  to  support  clinical  trials  and  research  and
development will continue to be significant in the future.

      To date, we have not marketed,  or generated  revenues from the commercial
sale of any products. Our biopharmaceutical  product candidates are not expected
to be  commercially  available for several  years,  if at all.  Accordingly,  we
expect to incur  operating  losses for the foreseeable  future.  There can be no
assurance that we will ever achieve profitable operations.

Critical Accounting Estimates

      The methods,  estimates  and  judgments we use in applying our  accounting
policies have a significant  impact on the results we report in our consolidated
financial statements, which we discuss under the heading "Results of Operations"
following this section of our Management's  Discussion and Analysis. Some of our
accounting policies require us to make difficult and subjective judgments, often
as a result  of the  need to make  estimates  of  matters  that  are  inherently
uncertain.  Our most critical  accounting  estimates  include the  assessment of
recoverability  of  goodwill,  which  could  impact  goodwill  impairments;  the
assessment of  recoverability  of long-lived  assets,  which  primarily  impacts
operating income if impairment exists. Below, we discuss these policies further,
as well as the estimates and judgments


                                       10


involved. Other key accounting policies, including revenue recognition, are less
subjective and involve a far lower degree of estimates and judgment.

Significant Accounting Policies

      The  following is a brief  discussion of the more  significant  accounting
policies and methods used by us in the preparation of our consolidated financial
statements.  Note  2 of  the  Notes  to the  Consolidated  Financial  Statements
includes a summary of all of the significant accounting policies.

      Share-based Compensation

The  Company  accounts  for its  stock-based  compensation  programs  under  the
provisions  of  Statement  of Financial  Accounting  Standards  No. 123 (revised
2004), "Share-Based Payment" ("SFAS 123(R)"), which requires the measurement and
recognition of compensation  expense for all share-based  payment awards made to
employees  and directors  including  employee  stock options and employee  stock
purchases   related  to  the  Employee  Stock  Purchase  Plan  ("employee  stock
purchases")  based on estimated fair values.  SFAS 123(R) requires  companies to
estimate the fair value of share-based  awards on the grant date using an option
pricing model. The value of the portion of the award that is ultimately expected
to vest is  recorded  as expense  over the  requisite  periods in the  Company's
consolidated statement of operations.

      Fair value of financial instruments

      The  carrying  value of cash and cash  equivalents,  accounts  payable and
accrued expenses approximates fair value due to the relatively short maturity of
these  instruments.  Common stock rights and warrants  which are  classified  as
assets or  liabilities  under the provisions of EITF 00-19 are recorded at their
fair  market  value  as of  each  reporting  period.  The  Company  applies  the
Black-Scholes  pricing model to calculate the fair values of common stock rights
and  warrants  using  the  contracted  term  of  the  instruments  and  expected
volatility  that is  calculated as a  combination  of the  Company's  historical
volatility and the volatility of a group of comparable companies.

      Revenue Recognition

      The Company  recognizes revenue from contract research and development and
research progress payments in accordance with SEC Staff Accounting  Bulletin No.
104,  Revenue  Recognition,  ("SAB 104"). In accordance with SAB 104, revenue is
recognized  when  persuasive  evidence of an  arrangement  exists,  delivery has
occurred,  the fee is  fixed  and  determinable,  collectibility  is  reasonably
assured,  contractual obligations have been satisfied and title and risk of loss
have been  transferred  to the  customer.  The Company  recognizes  revenue from
non-refundable  up-front payments,  not tied to achieving a specific performance
milestone, over the period which the Company is obligated to perform services or
based on the percentage of costs incurred to date,  estimated  costs to complete
and total expected  contract  revenue.  Payments for development  activities are
recognized as revenue is earned, over the period of effort.  Substantive at-risk
milestone  payments,  which  are  based  on  achieving  a  specific  performance
milestone,  are  recognized  as revenue  when the  milestone is achieved and the
related  payment  is  due,  providing  there  is no  future  service  obligation
associated with that milestone. In situations where the Company receives payment
in advance of the  performance  of  services,  such  amounts  are  deferred  and
recognized as revenue as the related services are performed.

      Goodwill

      Goodwill  is  recorded  when the  purchase  price paid for an  acquisition
exceeds the estimated fair value of the net  identified  tangible and intangible
assets acquired.

      The Company  evaluates  goodwill for  impairment  annually,  in the fourth
quarter  of each  year.  In  addition,  the  Company  would  test  goodwill  for
recoverability   between  annual  evaluations  whenever  events  or  changes  in
circumstances  indicate  that  the  carrying  amounts  may  not be  recoverable.
Examples of such events  could  include a  significant  adverse  change in legal
matters,  liquidity or in the business climate,  an adverse action or assessment
by a  regulator  or  government  organization,  loss  of key  personnel,  or new
circumstances  that would cause an  expectation  that it is more likely than not
that we would sell or otherwise dispose of a reporting unit. Goodwill impairment
is  determined  using a  two-step  approach  in  accordance  with  Statement  of
Financial  Accounting  Standards No. 142 "Goodwill and Other Intangible  Assets"
("SFAS  142").  The  impairment  review  process  compares the fair value of the
reporting unit in which  goodwill  resides to its carrying  value.  In 2006, the
Company operated as one business and one reporting unit. Therefore, the goodwill
impairment  analysis was  performed on the basis of the Company as a whole using
the market  capitalization  of the Company as an estimate of its fair value.  In
the past,  our market  capitalization  has been  significantly  in excess of the
Company's  carrying  value.  It is  reasonably  likely  that the  future  market
capitalization  of  SIGA  may  exceed  or  fall  short  of  our  current  market
capitalization, in which case a different amount for potential


                                       11


impairment would result. The use of the discounted expected future cash flows to
evaluate  the fair  value of the  Company  as a whole is  reasonably  likely  to
produce different results than the Company's market capitalization.

      Intangible Assets

      Acquisition-related  intangibles  at March 31,  2007,  represent  acquired
technology which is amortized on a straight line basis over a period of 2 years.

      In accordance  with  Statement of Financial  Accounting  Standards No. 144
"Accounting  for the Impairment or Disposal of Long-Lived  Assets" ("SFAS 144"),
the Company performs a review of its identified  intangible  assets to determine
if facts and circumstances  exist which indicate that the useful life is shorter
than  originally  estimated  or that the  carrying  amount of assets  may not be
recoverable.  If such facts and circumstances do exist, the Company assesses the
recoverability  of  identified  intangible  assets by  comparing  the  projected
undiscounted net cash flows associated with the related asset or group of assets
over  their  remaining  lives  against  their   respective   carrying   amounts.
Impairment,  if any, is based on the excess of the carrying amount over the fair
value of those assets.  Our  estimates of projected  cash flows are dependent on
many factors, including general economic trends,  technological developments and
projected future contracts and government  grants.  It is reasonably likely that
future cash flows associated with our intangible assets may exceed or fall short
of our  current  projections,  in which case a different  amount for  impairment
would  result.  If our actual  cash flows  exceed our  estimates  of future cash
flows,  any impairment  charge would be greater than needed.  If our actual cash
flows  are  less  than  our  estimated  cash  flows,  we may  need to  recognize
additional  impairment charges in future periods,  which would be limited to the
carrying amount of the intangible assets.

      Recent accounting pronouncements

      In February  2007, the FASB issued SFAS No. 159 "The Fair Value Option for
Financial  Assets  and  Financial  Liabilities"  ("FAS  159").  FAS 159  permits
entities to choose to measure  many  financial  assets and  liabilities  at fair
value. Unrealized gains and losses on items for which fair value option has been
elected  are  reported  in  earnings.  FAS 159 is  effective  for  fiscal  years
beginning after November 15, 2007. The Company is currently assessing the impact
of FAS 159 on its financial position and results of operations.

Results of Operations

Three months ended March 31, 2007 and 2006

      Revenues from research and development  contracts and grants for the three
months  ended  March  31,  2007 and 2006  were $1.9  million  and $1.4  million,
respectively.  Revenues  recorded  for the three  months  ended  March 31,  2007
increased  $0.5  million or 34% from the prior year.  For the three months ended
March 31,  2007 we  recorded  $1.2  million  from an NIH  contract  and NIH SBIR
grants,  supporting two of our lead programs.  Revenues from NIH SBIR grants and
an agreement with Saint Louis  University  supporting  these programs during the
three months ended March 31, 2006 were  $730,000.  The increase is mainly due to
revenue recognized from our 3 year, $16.5 million contract with the NIH. Revenue
recognized  from our  programs  with the USAF was  $630,000 and $550,000 for the
three months ended March 31, 2007 and 2006, respectively.

      Selling, general and administrative expenses ("SG&A") for the three months
ended March 31, 2007 and 2006 were  $877,000  and  $942,000,  respectively.  The
Company's  legal expenses for the three months ended March 31, 2007 increased by
$140,000  as  compared  to the same  period in 2006  mainly  due to our  defense
against an action filed against us by PharmAthene, Inc. This increase was offset
by a decline of $84,000 in  non-cash  stock-based  compensation.  The decline in
SG&A also  relates to a charge of $115,000  recorded by the Company on March 31,
2006, reflecting a severance payment to our former Chief Executive Officer.

      Research and  development  expenses were $2.6 million and $1.7 million for
the three  months ended March 31, 2007 and 2006,  respectively.  The increase of
approximately  $900,000 or 53% mainly reflects an increase in charges related to
clinical trials of our lead drug candidate  ST-246,  and higher payroll expenses
related to the expansion of the Company's  research and  development  work force
from 38 full time employees to 40 on March 31, 2007.

      During the three months ended March 31, 2007 and 2006,  we spent  $990,000
and  $402,000,  respectively,  on the  development  of our lead drug  candidate,
ST-246, an orally administered  anti-viral drug that targets the smallpox virus.
For the three months ended March 31, 2007, we spent  $171,000 on internal  human
resources and $820,000  mainly on clinical  testing.  For the three months ended
March 31, 2006, we spent  $191,000 on internal  human  resources and $211,000 on
pre-clinical testing of ST-246. From inception of the ST-246 development program
to-date,  we expended a


                                       12


total of $7.5  million  related to the  program,  of which $1.7 million and $5.8
million were spent on internal human  resources,  and clinical and  pre-clinical
work,  respectively.  These  resources  reflect SIGA's  research and development
expenses directly related to the program.  They exclude additional  expenditures
such as the cost to acquire the program,  patent  costs,  allocation of indirect
expenses, and the value of other services received from the NIH and the DoD.

      R&D expenses of $257,000 and $376,000  during the three months ended March
31, 2007 and 2006, respectively, were used to support the development of ST-294,
a drug candidate which has demonstrated  significant  antiviral activity in cell
culture assays against  arenavirus  pathogens,  as well as other drug candidates
for  hemorrhagic  fevers.  For the three months  ended March 31, 2007,  we spent
$59,000 on internal human resources and $198,000 mainly on pre-clinical testing.
For the three months ended March 31, 2006, we spent  $171,000 on internal  human
resources and $204,000 on pre-clinical  testing of ST-294. From inception of our
program to develop  ST-294 and other drug  candidates  for  hemorrhagic  fevers,
to-date,  we spent a total of $3.4 million related to the program, of which $1.6
million  and  $1.8  million  were  expended  on  internal  human  resources  and
pre-clinical  work,  respectively.  These resources  reflect SIGA's research and
development  expenses directly related to the program.  They exclude  additional
expenditures such as the cost to acquire the program,  patent costs,  allocation
of indirect expenses,  and the value of other services received from the NIH and
the DoD.

      R&D expenses related to our USAF Agreements were $251,000 and $171,000 for
internal  human  resources and external R&D services,  respectively,  during the
three  months  ended March 31,  2007.  During the same period in 2006,  we spent
$194,000 and $128,000 on internal  human  resources  and external R&D  services,
respectively.  Costs related to our work on the USAF Agreements, during the term
of the agreements to-date were $2.4 million,  of which we spent $1.1 million and
$1.3  million  on  internal   human   resources   and  external  R&D   services,
respectively.  These resources reflect SIGA's research and development  expenses
directly related to this agreement. They exclude additional expenditures such as
patent costs and allocation of indirect expenses.

      Our product programs are in the early stage of development.  At this stage
of development,  we cannot make  reasonable  estimates of the potential cost for
most of our  programs to be  completed  or the time it will take to complete the
project.  Our lead product,  ST-246, is an orally  administered  anti-viral drug
that  targets the  smallpox  virus.  In December  2005 the FDA  accepted our IND
application for ST-246 and granted it Fast-Track  status.  In December 2006, the
FDA granted Orphan Drug designation to ST-246,  for the prevention and treatment
of smallpox.  We expect that costs to complete the program will  approximate $15
million to $20 million,  and that the project could be completed in 24 months to
36 months.  There is a high risk of  non-completion  of any  program,  including
ST-246,  because of the lead time to program  completion and  uncertainty of the
costs.  Net cash  inflows from any  products  developed  from our programs is at
least one to three years away.  However,  we could  receive  additional  grants,
contracts or  technology  licenses in the  short-term.  The  potential  cash and
timing is not known and we cannot be certain if they will ever occur.

      The risk of failure to complete any program is high,  as each,  other than
our  smallpox  program  which began phase I clinical  trials in 2006,  is in the
relatively  early stage of  development.  Products  for the  biological  warfare
defense market, such as the ST-246 Smallpox anti-viral,  could generate revenues
in one to three years.  We believe the products  directed toward this market are
on  schedule.  We  expect  the  future  research  and  development  cost  of our
biological  warfare defense programs to increase as the potential products enter
animal studies and safety  testing,  including  human safety  trials.  Funds for
future  development will be partially paid for by NIH contracts and SBIR grants,
additional  government  funding and from future  financing.  If we are unable to
obtain  additional  federal  grants and  contracts  or  funding in the  required
amounts,  the development  timeline for these products would slow or possibly be
suspended.  Delay or  suspension  of any of our  programs  could have an adverse
impact on our ability to raise funds in the  future,  enter into  collaborations
with corporate  partners or obtain additional  federal funding from contracts or
grants.

      Patent preparation expenses for the three months ended March 31, 2007 were
$138,000  compared to $110,000 for the three  months  ended March 31,  2006.  We
incurred  higher costs during the 2007 three months period for work performed in
connection with our two lead programs.

      In  connection  with the sale of  common  stock,  warrants  and  rights in
October  2006 and  November  2005,  we recorded a loss for the  increase in fair
market value of common stock rights and common stock  warrants.  The warrants to
purchase  common stock of SIGA were recorded at fair market value and classified
as  liabilities  at the  time of the  transaction.  A loss of $1.5  million  was
recorded by us in each of the three month periods reflecting the increase in the
fair value of  warrants  and rights to acquire  additional  shares of our common
stock, from the respective year ends.

      Other  income of $114,000  and $6,000 for the three months ended March 31,
2007 and 2006, respectively, reflect interest income for the period.


                                       13


Liquidity and Capital Resources

      On March  31,  2007,  we had $9.7  million  in cash and cash  equivalents.
During the first  quarter of 2007, we received net proceeds of $1.1 million from
exercises of warrants  and options to purchase  shares of the  Company's  Common
stock.

      We believe that our existing cash combined  with  anticipated  cash flows,
including receipt of future funding from government contracts and grants will be
sufficient to support our  operations  beyond the next twelve  months,  and that
sufficient cash flows will be available to meet our business  objectives  during
that period.

      Operating activities

      Net cash used in  operations  during the three months ended March 31, 2007
was $2.0 million compared to $40,000  generated from operations during the three
months  ended March 31, 2006.  During the three months ended March 31, 2006,  we
received two advance  payments  from the USAF for a total of $1.5  million.  Our
current  agreements with the USAF do not include advance payments.  In addition,
during the first three months of 2007, our accounts receivable balance increased
$662,000,  compared with a collection of $625,000 of accounts  receivable during
the same period in 2006.

      Investing activities

      Capital expenditures during the three months ended March 31, 2007 and 2006
were $40,000 and $307,000,  respectively,  and mainly  supported  acquisition of
laboratory  equipment in 2007 and the  renovation  of our  research  facility in
Oregon during the same period in 2006.

      Financing activities

      Cash  provided by financing  activities  was $1.1 million and $1.0 million
during the three months ended March 31, 2007 and 2006, respectively.  During the
three months ended March 31, 2007 we received  $1.1 million from the exercise of
options and warrants to purchase shares of common stock. During the three months
ended March 31, 2006, we received  proceeds of $1.0 million under a note payable
to PharmAthene, Inc. The note was paid off in October 2006.

      We have  incurred  cumulative  net losses  and expect to incur  additional
losses to perform further  research and development  activities.  We do not have
commercial products and have limited capital resources. Our plans with regard to
these matters include  continued  development of our products as well as seeking
additional  working capital through a combination of  collaborative  agreements,
strategic  alliances,  research grants,  equity and debt financing.  Although we
continue to pursue these plans, there is no assurance that we will be successful
in obtaining future financing on commercially reasonable terms.

      Our working  capital and capital  requirements  will depend upon  numerous
factors,   including   pharmaceutical   research   and   development   programs;
pre-clinical  and  clinical  testing;  timing and cost of  obtaining  regulatory
approvals;   levels  of  resources   that  we  devote  to  the   development  of
manufacturing  and marketing  capabilities;  technological  advances;  status of
competitors;  and our ability to establish collaborative arrangements with other
organizations.

Off-Balance Sheet Arrangements

      SIGA does not have any off-balance sheet arrangements.

Safe Harbor Statement

      This  report  contains  certain  "forward-looking  statements"  within the
meaning of the Private  Securities  Litigation  Reform Act of 1995,  as amended,
including statements regarding the efficacy of potential products, the timelines
for bringing such products to market and the availability of funding sources for
continued development of such products.  Forward-looking statements are based on
management's  estimates,   assumptions  and  projections,  and  are  subject  to
uncertainties,  many of which are beyond the control of SIGA. Actual results may
differ  materially  from those  anticipated  in any  forward-looking  statement.
Factors  that may cause such  differences  include the risks that (a)  potential
products that appear promising to SIGA or its  collaborators  cannot be shown to
be efficacious or safe in subsequent  pre-clinical or clinical trials,  (b) SIGA
or its  collaborators  will not obtain  appropriate  or  necessary  governmental
approvals to


                                       14


market  these or other  potential  products,  (c) SIGA may not be able to obtain
anticipated  funding for its development  projects or other needed funding,  (d)
SIGA may not be able to secure funding from anticipated government contracts and
grants, (e) SIGA may not be able to secure or enforce adequate legal protection,
including patent  protection,  for its products and (f)  unanticipated  internal
control  deficiencies  or  weaknesses  or  ineffective  disclosure  controls and
procedures.  More  detailed  information  about SIGA and risk  factors  that may
affect  the   realization   of   forward-looking   statements,   including   the
forward-looking statements in this presentation,  is set forth in SIGA's filings
with the Securities and Exchange  Commission,  including SIGA's Annual Report on
Form 10-K for the fiscal year ended  December 31, 2006,  and in other  documents
that SIGA has filed with the  Commission.  SIGA  urges  investors  and  security
holders to read those documents free of charge at the  Commission's  Web site at
http://www.sec.gov.  Interested  parties may also obtain those documents free of
charge from SIGA.  Forward-looking statements speak only as of the date they are
made, and except for our ongoing  obligations under the U.S. federal  securities
laws,  we  undertake  no  obligation  to  publicly  update  any  forward-looking
statements whether as a result of new information, future events or otherwise.


                                       15


Item 3. Quantitative and Qualitative Disclosure About Market Risk

      None

Item 4. Controls and Procedures

      (a) Disclosure Controls and Procedures. The Company's management, with the
participation  of the  Company's  Chief  Financial  Officer,  has  evaluated the
effectiveness of the Company's disclosure controls and procedures (as defined in
Rules  13a-15(e)  and  15d-15(e)  under the  Exchange  Act) as of the end of the
fiscal period  covered by this  Quarterly  Report on Form 10-Q.  Based upon such
evaluation,  the Chief  Executive  Officer  and  Chief  Financial  Officer  have
concluded that, as of the end of such period, the Company's  disclosure controls
and procedures are effective.

      (b) Internal  Control Over  Financial  Reporting.  There have not been any
changes in the Company's internal control over financial reporting (as such term
is defined in Rules  13a-15(f) and 15d-15(f)  under the Exchange Act) during the
fiscal period covered by this Quarterly Report on Form 10-Q that have materially
affected,  or are reasonably likely to materially affect, the Company's internal
control over financial reporting.


                                       16


                                     Part II
                                Other information

Item 1.  On December 20, 2006, PharmAthene, Inc. ("PharmAthene") filed an action
         against the Company in the Court of Chancery in the State of  Delaware,
         captioned  PharmAthene,  Inc.  v. SIGA  Technologies,  Inc.,  C.A.  No.
         2627-N.  In its  Complaint,  PharmAthene  asks the  Court to order  the
         Company to enter into a license agreement with PharmAthene with respect
         to SIGA-246, as well as issue a declaration that the Company is obliged
         to execute such a license  agreement,  and award damages resulting from
         the Company's  supposed  breach of that  obligation.  PharmAthene  also
         alleges that the Company  breached an  obligation  to negotiate  such a
         license  agreement  in  good  faith,  as  well  as  seeks  damages  for
         promissory   estoppel   and  unjust   enrichment   based  on   supposed
         information, capital and assistance that PharmAthene allegedly provided
         to the Company during the negotiation  process. On January 9, 2007, the
         Company  filed a motion to dismiss the  Complaint  in its  entirety for
         failure to state a claim upon which  relief can be granted.  The motion
         has been fully  briefed and oral  argument is currently  scheduled  for
         June 1, 2007.  On January 19, 2007,  PharmAthene  served on the Company
         its first request for  production  of  documents.  The Company moved to
         stay discovery on January 26, 2007 and this motion was granted on March
         8, 2007.  SIGA  believes that the claims are without merit and plans to
         defend itself vigorously.

Item 1A. Risk Factors - There were no material changes to Risk Factors disclosed
         in SIGA's 2006 Form 10-K.

Item 2.  Unregistered Sale of Equity Securities and Use of Proceeds - None.

Item 3.  Defaults upon Senior Securities - None.

Item 4.  Submission of Matters to a Vote of Security Holders - None.

Item 5.  Other Information - None.

Item 6.  Exhibits

     *   31    Certification  of  Chief  Executive   Officer  and  Acting  Chief
               Executive  Officer Pursuant to Section 302 of the  Sarbanes-Oxley
               Act of 2002.

     *   31    Certification  of  Chief  Financial   Officer  and  Acting  Chief
               Executive  Officer Pursuant to Section 302 of the  Sarbanes-Oxley
               Act of 2002.

     *   32    Certification  of  Chief  Executive   Officer  and  Acting  Chief
               Executive  Officer Pursuant to Section 906 of the  Sarbanes-Oxley
               Act of 2002.

     *   32    Certification  of  Chief  Financial   Officer  and  Acting  Chief
               Executive  Officer Pursuant to Section 906 of the  Sarbanes-Oxley
               Act of 2002.

         * Filed herein


                                       17


                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.

                                                     SIGA Technologies, Inc.
                                                     (Registrant)

         Date: May 7, 2007                           By:/s/ Thomas N. Konatich
                                                        ------------------------
                                                     Thomas N. Konatich
                                                     Chief Financial Officer


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