Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Mahatme Sandesh
  2. Issuer Name and Ticker or Trading Symbol
Sarepta Therapeutics, Inc. [SRPT]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
EVP, CFO & CBO
(Last)
(First)
(Middle)
215 FIRST STREET, SUITE 415
3. Date of Earliest Transaction (Month/Day/Year)
01/30/2019
(Street)

CAMBRIDGE, MA 02142
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 01/30/2019   M(1)   5,469 A $ 13.71 14,118 D  
Common Stock 01/30/2019   M(1)   1,128 A $ 13.71 15,246 D  
Common Stock 01/30/2019   M(1)   17,860 A $ 13.9 33,106 D  
Common Stock 01/30/2019   M(1)   19,345 A $ 23.85 52,451 D  
Common Stock 01/30/2019   S(1)   43,802 D $ 130 8,649 D  
Common Stock 01/31/2019   M(1)   21,198 A $ 23.85 29,847 D  
Common Stock 01/31/2019   S(1)   21,198 D $ 130.72 8,649 D  
Common Stock               12,012 I By trust

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy) $ 13.71 01/30/2019   M(1)     5,469 02/28/2017 02/28/2026 Common Stock 5,469 $ 0 7,404 D  
Stock Option (right to buy) $ 13.71 01/30/2019   M(1)     1,128 02/28/2017 02/28/2026 Common Stock 1,128 $ 0 6,771 D  
Stock Option (right to buy) $ 13.9 01/30/2019   M(1)     17,860 02/27/2016 02/27/2025 Common Stock 17,860 $ 0 0 D  
Stock Option (right to buy) $ 23.85 01/30/2019   M(1)     19,345 11/05/2013 11/05/2022 Common Stock 19,345 $ 0 96,664 D  
Stock Option (right to buy) $ 23.85 01/31/2019   M(1)     21,198 11/05/2013 11/05/2022 Common Stock 21,198 $ 0 75,466 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Mahatme Sandesh
215 FIRST STREET, SUITE 415
CAMBRIDGE, MA 02142
      EVP, CFO & CBO  

Signatures

 /s/ David Tyronne Howton, as attorney-in-fact for Sandesh Mahatme   02/01/2019
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) This transaction was effected pursuant to a Rule 10b5-1 Plan. Accordingly, the reporting person had no discretion with regards to the timing of the transaction.

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