Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
MAZZO JAMES V
  2. Issuer Name and Ticker or Trading Symbol
ADVANCED MEDICAL OPTICS INC [EYE]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chairman, President and CEO
(Last)
(First)
(Middle)
C/O ADVANCED MEDICAL OPTICS, INC., 1700 E. ST. ANDREW PLACE
3. Date of Earliest Transaction (Month/Day/Year)
04/27/2007
(Street)

SANTA ANA, CA 92705
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock               17,817.5287 (1) D  
Common Stock 04/27/2007   M(2)   91,932 A $ 13.715 179,810 I By Family Trust
Common Stock 04/27/2007   S(2)   71,430 D $ 41.3148 108,380 I By Family Trust
Common Stock               1,488.2603 I By 401(k) Trust (as of 2/7/07)
Common Stock               16 I By child
Common Stock               7.6924 I By Spouse (3)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (Right to Buy) $ 13.715 04/27/2007   M(2)     91,932 02/02/2005 02/02/2008 Common Stock 91,932 $ 0 0 I By Family Trust

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
MAZZO JAMES V
C/O ADVANCED MEDICAL OPTICS, INC.
1700 E. ST. ANDREW PLACE
SANTA ANA, CA 92705
  X     Chairman, President and CEO  

Signatures

 James V. Mazzo, By: Aimee S. Weisner, Attorney-in-Fact   04/30/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Includes an aggregate of 5,017.5287 shares acquired under the Advanced Medical Optics, Inc. Employee Stock Purchase Plan ("ESPP") through the purchase period that ended on October 31, 2006.
(2) This Form 4 reports transactions effected pursuant to a Rule 10b5-1 trading plan ("Plan") that was entered into by the reporting person on February 18, 2005. Pursuant to the Plan, the reporting person (a) exercised a Rule 16b3 exempt stock option that had been granted on February 2, 2001, and which would have expired on February 2, 2008 if not sooner exercised by the reporting person, and (b) sold only such number of the shares acquired thereby as were necessary to satisfy the option's exercise price and associated taxes, as well as to net an amount sufficient to repay a relocation loan made by the issuer on July 2, 2002. The net result of these transactions is that the family trust of the reproting person has acquired an additional 20,502 shares of the issuers' common stock.
(3) An aggregate of 100 shares have been acquired by a stock club in which Mrs. Keleen B. Mazzo (spouse of Mr. James V. Mazzo) is one of thirteen members. Mr. Mazzo disclaims beneficial ownership of these securities and this report shall not be deemed an admission that Mr. Mazzo is the beneficial owner of such securities for purposes of Section 16 or any other purpose.

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