UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                                   FORM 13F

                             FORM 13F COVER PAGE

Report for the Calendar Year or Quarter Ended: June 30, 2006

Check here if Amendment [ ]; Amendment Number:
This Amendment (Check only one.): [ ] is a restatement.
                                  [ ] adds new holdings entries.

Institutional Investment Manager Filing this Report:

Name:GENERAL AMERICAN INVESTORS COMPANY, INC. 13F File No. 28-461
Address: 450 Lexington Ave, Suite 3300
         New York, NY 10017

13F File Number: 28-461

The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing the report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables, are considered integral parts of this form.


Person Signing this Report on Behalf of Reporting Manager:

Name: Eugene S. Stark
Title: Vice-President, Administration
Phone: 212-916-8447
Signature, Place, and Date of Signing:

  Eugene S. Stark   New York, NY   June 30, 2006


Report Type (Check only one.):

[X]    13F HOLDINGS REPORT.

[ ]    13F NOTICE.

[ ]    13F COMBINATION REPORT.


List of Other Managers Reporting for this Manager:

        Form 13F File Number                Name


I AM SIGNING THIS REPORT AS REQUIRED BY THE SECURITIES EXCHANGE ACT OF 1934.


FORM 13F SUMMARY PAGE


Report Summary:

Number of Other Included Managers:       0

Form 13F Information Table Entry Total:  57

Form 13F Information Table Value Total:  $1224452720



List of Other Included Managers:

No.   13F File Number    Name






   COLUMN 1                           COLUMN 2     COLUMN 3   COLUMN 4      COLUMN 5    COLUMN 6  COLUMN 7            COLUMN 8
---------------                      ----------   ---------- ---------     ----------   --------- -------           -----------
                                                             VALUE    SHARES/ SH/ PUT/ INVSTMT    OTHER   -----VOTING AUTHORITY-----
  NAME OF ISSUER                 -TITLE OF CLASS- --CUSIP-- x$1000    PRN AMT PRN CALL DSCRETN -MANAGERS-     SOLE   SHARED     NONE
                                                                                                      
ABB Ltd. ADR                     COMMON           000375204    14904  1150000 SH       SOLE                1150000        0        0
Arch Capital Group Ltd.          COMMON           G0450A105    20811   350000 SH       SOLE                 350000        0        0
Adams Express Company            COMMON           006212104     1352   105075 SH       SOLE                 105075        0        0
American International Group,Inc COMMON           026874107    20668   350000 SH       SOLE                 350000        0        0
Alkermes, Inc.                   COMMON           01642T108     4541   240000 SH       SOLE                 240000        0        0
The Allstate Corporation         COMMON           020002101    15051   275000 SH       SOLE                 275000        0        0
American Tower Corporation       COMMON           029912201    24118   775000 SH       SOLE                 775000        0        0
Apache Corporation               COMMON           037411105    56306   825000 SH       SOLE                 825000        0        0
Avaya Inc.                       COMMON           053499109     4340   380000 SH       SOLE                 380000        0        0
AXIS Capital Holdings Limited    COMMON           G0692U109    11444   400000 SH       SOLE                 400000        0        0
Bank of America Corporation      COMMON           060505104    13468   280000 SH       SOLE                 280000        0        0
Bed Bath & Beyond Inc.           COMMON           075896100     6634   200000 SH       SOLE                 200000        0        0
Bancroft Convertible Fund        COMMON           059695106      394    21374 SH       SOLE                  21374        0        0
Biogen Idec Inc.                 COMMON           09062X103     7874   170000 SH       SOLE                 170000        0        0
Berkshire Hathaway Inc. Class A  COMMON           084670108    27498      300 SH       SOLE                    300        0        0
Brooks Automation, Inc.          COMMON           114340102     2631   223000 SH       SOLE                 223000        0        0
Cephalon, Inc.                   COMMON           156708109     9015   150000 SH       SOLE                 150000        0        0
Central Securities Corporation   COMMON           155123102      660    26055 SH       SOLE                  26055        0        0
Costco Wholesale Corporation     COMMON           22160K105    39991   700000 SH       SOLE                 700000        0        0
Cisco Systems, Inc.              COMMON           17275R102    17577   900000 SH       SOLE                 900000        0        0
CEMEX, S.A. de C.V. ADR          COMMON           151290889    66964  1175431 SH       SOLE                1175431        0        0
Cytokinetics, Incorporated       COMMON           23282W100     3805   604900 SH       SOLE                 604900        0        0
Diageo plc ADR                   COMMON           25243Q205    23643   350000 SH       SOLE                 350000        0        0
Dollar General Corporation       COMMON           256669102    27261  1950000 SH       SOLE                1950000        0        0
Genentech, Inc.                  COMMON           368710406    19632   240000 SH       SOLE                 240000        0        0
EMC Corporation                  COMMON           268648102     3291   300000 SH       SOLE                 300000        0        0
Golden West Financial            COMMON           381317106    43407   585000 SH       SOLE                 585000        0        0
Halliburton Company              COMMON           406216101    29684   400000 SH       SOLE                 400000        0        0
The Home Depot, Inc.             COMMON           437076102    56190  1570000 SH       SOLE                1570000        0        0
Hydril Company                   COMMON           448774109     4319    55000 SH       SOLE                  55000        0        0
Intermec, Inc.                   COMMON           458786100     1950    85000 SH       SOLE                  85000        0        0
Lamar Advertising Company        COMMON           512815101    18851   350000 SH       SOLE                 350000        0        0
Medtronic, Inc.                  COMMON           585055106    21114   450000 SH       SOLE                 450000        0        0
MedImmune, Inc.                  COMMON           584699102    10298   380000 SH       SOLE                 380000        0        0
MetLife, Inc.                    COMMON           59156R108    14595   285000 SH       SOLE                 285000        0        0
MFA Mortgage Investments, Inc.   COMMON           55272X102     7912  1150000 SH       SOLE                1150000        0        0
Molex Incorporated Class A       COMMON           608554200    15802   550000 SH       SOLE                 550000        0        0
Microsoft Corporation            COMMON           594918104    32620  1400000 SH       SOLE                1400000        0        0
M&T Bank Corporation             COMMON           55261F104    36555   310000 SH       SOLE                 310000        0        0
Annaly Mortgage Management, Inc. COMMON           035710409     8391   655000 SH       SOLE                 655000        0        0
PepsiCo, Inc.                    COMMON           713448108    10507   175000 SH       SOLE                 175000        0        0
Pfizer Inc                       COMMON           717081103    42528  1812000 SH       SOLE                1812000        0        0
PartnerRe Ltd.                   COMMON           G6852T105    23378   365000 SH       SOLE                 365000        0        0
Patterson-UTI Energy, Inc.       COMMON           703481101    28310  1000000 SH       SOLE                1000000        0        0
Everest Re Group, Ltd.           COMMON           G3223R108    49778   575000 SH       SOLE                 575000        0        0
Republic Services, Inc.          COMMON           760759100    47400  1175000 SH       SOLE                1175000        0        0
Rio Tinto plc ADR                COMMON           767204100    13631    65000 SH       SOLE                  65000        0        0
Royce Value Trust                COMMON           780910105     2277   117608 SH       SOLE                 117608        0        0
SunTrust Banks, Inc.             COMMON           867914103    13727   180000 SH       SOLE                 180000        0        0
Constellation Brands, Inc.       COMMON           21036P108     6875   275000 SH       SOLE                 275000        0        0
The TJX Companies, Inc.          COMMON           872540109    57150  2500000 SH       SOLE                2500000        0        0
Talisman Energy Inc.             COMMON           87425E103    52440  3000000 SH       SOLE                3000000        0        0
Transatlantic Holdings, Inc.     COMMON           893521104    13137   235000 SH       SOLE                 235000        0        0
VeriSign, Inc.                   COMMON           92343E102     3093   133500 SH       SOLE                 133500        0        0
Weatherford International Ltd.   COMMON           G95089101    60536  1220000 SH       SOLE                1220000        0        0
Wal-Mart Stores, Inc.            COMMON           931142103    27698   575000 SH       SOLE                 575000        0        0
Xerox Corporation                COMMON           984121103    26429  1900000 SH       SOLE                1900000        0        0