UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F COVER PAGE Report for the Calendar Year or Quarter Ended: June 30, 2006 Check here if Amendment [ ]; Amendment Number: This Amendment (Check only one.): [ ] is a restatement. [ ] adds new holdings entries. Institutional Investment Manager Filing this Report: Name:GENERAL AMERICAN INVESTORS COMPANY, INC. 13F File No. 28-461 Address: 450 Lexington Ave, Suite 3300 New York, NY 10017 13F File Number: 28-461 The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form. Person Signing this Report on Behalf of Reporting Manager: Name: Eugene S. Stark Title: Vice-President, Administration Phone: 212-916-8447 Signature, Place, and Date of Signing: Eugene S. Stark New York, NY June 30, 2006 Report Type (Check only one.): [X] 13F HOLDINGS REPORT. [ ] 13F NOTICE. [ ] 13F COMBINATION REPORT. List of Other Managers Reporting for this Manager: Form 13F File Number Name I AM SIGNING THIS REPORT AS REQUIRED BY THE SECURITIES EXCHANGE ACT OF 1934. FORM 13F SUMMARY PAGE Report Summary: Number of Other Included Managers: 0 Form 13F Information Table Entry Total: 57 Form 13F Information Table Value Total: $1224452720 List of Other Included Managers: No. 13F File Number Name COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8 --------------- ---------- ---------- --------- ---------- --------- ------- ----------- VALUE SHARES/ SH/ PUT/ INVSTMT OTHER -----VOTING AUTHORITY----- NAME OF ISSUER -TITLE OF CLASS- --CUSIP-- x$1000 PRN AMT PRN CALL DSCRETN -MANAGERS- SOLE SHARED NONE ABB Ltd. ADR COMMON 000375204 14904 1150000 SH SOLE 1150000 0 0 Arch Capital Group Ltd. COMMON G0450A105 20811 350000 SH SOLE 350000 0 0 Adams Express Company COMMON 006212104 1352 105075 SH SOLE 105075 0 0 American International Group,Inc COMMON 026874107 20668 350000 SH SOLE 350000 0 0 Alkermes, Inc. COMMON 01642T108 4541 240000 SH SOLE 240000 0 0 The Allstate Corporation COMMON 020002101 15051 275000 SH SOLE 275000 0 0 American Tower Corporation COMMON 029912201 24118 775000 SH SOLE 775000 0 0 Apache Corporation COMMON 037411105 56306 825000 SH SOLE 825000 0 0 Avaya Inc. COMMON 053499109 4340 380000 SH SOLE 380000 0 0 AXIS Capital Holdings Limited COMMON G0692U109 11444 400000 SH SOLE 400000 0 0 Bank of America Corporation COMMON 060505104 13468 280000 SH SOLE 280000 0 0 Bed Bath & Beyond Inc. COMMON 075896100 6634 200000 SH SOLE 200000 0 0 Bancroft Convertible Fund COMMON 059695106 394 21374 SH SOLE 21374 0 0 Biogen Idec Inc. COMMON 09062X103 7874 170000 SH SOLE 170000 0 0 Berkshire Hathaway Inc. Class A COMMON 084670108 27498 300 SH SOLE 300 0 0 Brooks Automation, Inc. COMMON 114340102 2631 223000 SH SOLE 223000 0 0 Cephalon, Inc. COMMON 156708109 9015 150000 SH SOLE 150000 0 0 Central Securities Corporation COMMON 155123102 660 26055 SH SOLE 26055 0 0 Costco Wholesale Corporation COMMON 22160K105 39991 700000 SH SOLE 700000 0 0 Cisco Systems, Inc. COMMON 17275R102 17577 900000 SH SOLE 900000 0 0 CEMEX, S.A. de C.V. ADR COMMON 151290889 66964 1175431 SH SOLE 1175431 0 0 Cytokinetics, Incorporated COMMON 23282W100 3805 604900 SH SOLE 604900 0 0 Diageo plc ADR COMMON 25243Q205 23643 350000 SH SOLE 350000 0 0 Dollar General Corporation COMMON 256669102 27261 1950000 SH SOLE 1950000 0 0 Genentech, Inc. COMMON 368710406 19632 240000 SH SOLE 240000 0 0 EMC Corporation COMMON 268648102 3291 300000 SH SOLE 300000 0 0 Golden West Financial COMMON 381317106 43407 585000 SH SOLE 585000 0 0 Halliburton Company COMMON 406216101 29684 400000 SH SOLE 400000 0 0 The Home Depot, Inc. COMMON 437076102 56190 1570000 SH SOLE 1570000 0 0 Hydril Company COMMON 448774109 4319 55000 SH SOLE 55000 0 0 Intermec, Inc. COMMON 458786100 1950 85000 SH SOLE 85000 0 0 Lamar Advertising Company COMMON 512815101 18851 350000 SH SOLE 350000 0 0 Medtronic, Inc. COMMON 585055106 21114 450000 SH SOLE 450000 0 0 MedImmune, Inc. COMMON 584699102 10298 380000 SH SOLE 380000 0 0 MetLife, Inc. COMMON 59156R108 14595 285000 SH SOLE 285000 0 0 MFA Mortgage Investments, Inc. COMMON 55272X102 7912 1150000 SH SOLE 1150000 0 0 Molex Incorporated Class A COMMON 608554200 15802 550000 SH SOLE 550000 0 0 Microsoft Corporation COMMON 594918104 32620 1400000 SH SOLE 1400000 0 0 M&T Bank Corporation COMMON 55261F104 36555 310000 SH SOLE 310000 0 0 Annaly Mortgage Management, Inc. COMMON 035710409 8391 655000 SH SOLE 655000 0 0 PepsiCo, Inc. COMMON 713448108 10507 175000 SH SOLE 175000 0 0 Pfizer Inc COMMON 717081103 42528 1812000 SH SOLE 1812000 0 0 PartnerRe Ltd. COMMON G6852T105 23378 365000 SH SOLE 365000 0 0 Patterson-UTI Energy, Inc. COMMON 703481101 28310 1000000 SH SOLE 1000000 0 0 Everest Re Group, Ltd. COMMON G3223R108 49778 575000 SH SOLE 575000 0 0 Republic Services, Inc. COMMON 760759100 47400 1175000 SH SOLE 1175000 0 0 Rio Tinto plc ADR COMMON 767204100 13631 65000 SH SOLE 65000 0 0 Royce Value Trust COMMON 780910105 2277 117608 SH SOLE 117608 0 0 SunTrust Banks, Inc. COMMON 867914103 13727 180000 SH SOLE 180000 0 0 Constellation Brands, Inc. COMMON 21036P108 6875 275000 SH SOLE 275000 0 0 The TJX Companies, Inc. COMMON 872540109 57150 2500000 SH SOLE 2500000 0 0 Talisman Energy Inc. COMMON 87425E103 52440 3000000 SH SOLE 3000000 0 0 Transatlantic Holdings, Inc. COMMON 893521104 13137 235000 SH SOLE 235000 0 0 VeriSign, Inc. COMMON 92343E102 3093 133500 SH SOLE 133500 0 0 Weatherford International Ltd. COMMON G95089101 60536 1220000 SH SOLE 1220000 0 0 Wal-Mart Stores, Inc. COMMON 931142103 27698 575000 SH SOLE 575000 0 0 Xerox Corporation COMMON 984121103 26429 1900000 SH SOLE 1900000 0 0