Form N-Q

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM N-Q


QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED MANAGEMENT INVESTMENT COMPANY

Investment Company Act file number         811-21213         

        Nuveen Insured Tax-Free Advantage Municipal Fund         
(Exact name of registrant as specified in charter)

Nuveen Investments
        333 West Wacker Drive, Chicago, Illinois 60606         
(Address of principal executive offices) (Zip code)


Kevin J. McCarthy Vice President and Secretary
        333 West Wacker Drive, Chicago, Illinois 60606         
(Name and address of agent for service)

Registrant's telephone number, including area code:         312-917-7700        

Date of fiscal year end:            10/31          

Date of reporting period:         7/31/08         

Form N-Q is to be used by management investment companies, other than small business investment companies registered on Form N-5 (§§ 239.24 and 274.5 of this chapter), to file reports with the Commission, not later than 60 days after the close of the first and third fiscal quarters, pursuant to rule 30b1-5 under the Investment Company Act of 1940 (17 CFR 270.30b1-5). The Commission may use the information provided on Form N-Q in its regulatory, disclosure review, inspection, and policymaking roles.

A registrant is required to disclose the information specified by Form N-Q, and the Commission will make this information public. A registrant is not required to respond to the collection of information contained in Form N-Q unless the Form displays a currently valid Office of Management and Budget ("OMB") control number. Please direct comments concerning the accuracy of the information collection burden estimate and any suggestions for reducing the burden to the Secretary, Securities and Exchange Commission, 450 Fifth Street, NW, Washington, DC 20549-0609. The OMB has reviewed this collection of information under the clearance requirements of 44 U.S.C. § 3507.

Item 1. Schedule of Investments

    Portfolio of Investments (Unaudited)             
    Nuveen Insured Tax-Free Advantage Municipal Fund (NEA)             
    July 31, 2008             
Principal        Optional Call         
Amount (000)    Description (1)    Provisions (2)    Ratings (3)    Value 
    Alabama – 8.8% (5.5% of Total Investments)             
$           1,000    Alabama Special Care Facilities Financing Authority, Revenue Bonds, Ascension Health, Series 2006C-2,    11/16 at 100.00    AA   $  969,035 
     5.000%, 11/15/36 (UB)             
5,655    Colbert County-Northwest Health Care Authority, Alabama, Revenue Bonds, Helen Keller Hospital,    6/13 at 101.00    Baa3    5,338,037 
     Series 2003, 5.750%, 6/01/27             
3,100    Huntsville Healthcare Authority, Alabama, Revenue Bonds, Series 1998A, 5.400%, 6/01/22    5/12 at 102.00    AA (4)    3,408,605 
     (Pre-refunded 5/14/12) – MBIA Insured             
6,280    Jefferson County, Alabama, Sewer Revenue Capital Improvement Warrants, Series 2002D, 5.000%,    8/12 at 100.00    AAA    6,773,482 
     2/01/32 (Pre-refunded 8/01/12) – FGIC Insured             
1,750    Montgomery, Alabama, General Obligation Warrants, Series 2003, 5.000%, 5/01/21 – AMBAC Insured    5/12 at 101.00    AA    1,798,598 
4,500    Sheffield, Alabama, Electric Revenue Bonds, Series 2003, 5.500%, 7/01/29 – AMBAC Insured    7/13 at 100.00    Aa3    4,587,975 
22,285    Total Alabama            22,875,732 
    Arizona – 5.4% (3.4% of Total Investments)             
10,000    Maricopa County Pollution Control Corporation, Arizona, Revenue Bonds, Arizona Public Service    11/12 at 100.00    AA    8,954,300 
     Company – Palo Verde Project, Series 2002A, 5.050%, 5/01/29 – AMBAC Insured             
6,545    Phoenix, Arizona, Civic Improvement Revenue Bonds, Civic Plaza, Series 2005B, 0.000%,    No Opt. Call    AA    5,037,163 
     7/01/37 – FGIC Insured             
16,545    Total Arizona            13,991,463 
    California – 30.2% (18.9% of Total Investments)             
26,300    California State Public Works Board, Lease Revenue Bonds, Department of General Services,    12/12 at 100.00    AA    26,073,028 
     Capital East End Project, Series 2002A, 5.000%, 12/01/27 – AMBAC Insured             
250    California State, General Obligation Bonds, Series 2002, 5.250%, 4/01/30 – XLCA Insured    4/12 at 100.00    A1    252,470 
10,000    California State, General Obligation Bonds, Series 2002, 5.250%, 4/01/30 (Pre-refunded    4/12 at 100.00    A1 (4)    10,860,500 
     4/01/12) – XLCA Insured             
5    California State, General Obligation Bonds, Series 2004, 5.000%, 4/01/31 – AMBAC Insured    4/14 at 100.00    AA    4,940 
7,495    California State, General Obligation Bonds, Series 2004, 5.000%, 4/01/31 (Pre-refunded    4/14 at 100.00    AAA    8,213,246 
     4/01/14) – AMBAC Insured             
2,910    Cathedral City Public Financing Authority, California, Tax Allocation Bonds, Housing    8/12 at 102.00    AA    2,944,571 
     Set-Aside, Series 2002D, 5.000%, 8/01/26 – MBIA Insured             
250    Golden State Tobacco Securitization Corporation, California, Enhanced Tobacco Settlement    6/17 at 100.00    BBB    184,555 
     Asset-Backed Bonds, Series 2007A-1, 5.125%, 6/01/47             
8,000    Golden State Tobacco Securitization Corporation, California, Tobacco Settlement Asset-Backed    6/15 at 100.00    A    7,244,560 
     Revenue Bonds, Series 2005A, 5.000%, 6/01/35 – FGIC Insured (UB)             
2,500    Irvine Public Facilities and Infrastructure Authority, California, Assessment Revenue Bonds,    9/13 at 100.00    AA    2,545,925 
     Series 2003C, 5.000%, 9/02/23 – AMBAC Insured             
4,000    Montara Sanitation District, California, General Obligation Bonds, Series 2003, 5.000%,    8/11 at 101.00    A+    3,935,440 
     8/01/28 – FGIC Insured             
    Plumas County, California, Certificates of Participation, Capital Improvement Program,             
    Series 2003A:             
1,130     5.250%, 6/01/19 – AMBAC Insured    6/13 at 101.00    AA    1,171,754 
1,255     5.250%, 6/01/21 – AMBAC Insured    6/13 at 101.00    AA    1,284,505 
1,210    Redding Joint Powers Financing Authority, California, Lease Revenue Bonds, Capital Improvement    3/13 at 100.00    AA    1,223,782 
     Projects, Series 2003A, 5.000%, 3/01/23 – AMBAC Insured             
3,750    Sacramento Municipal Utility District, California, Electric Revenue Bonds, Series 2003R,    8/13 at 100.00    AA    3,661,800 
     5.000%, 8/15/28 – MBIA Insured             
1,500    San Diego Community College District, California, General Obligation Bonds, Series 2003A,    5/13 at 100.00    AAA    1,521,405 
     5.000%, 5/01/28 – FSA Insured             
1,055    Turlock Irrigation District, California, Certificates of Participation, Series 2003A, 5.000%,    1/13 at 100.00    AA    1,044,608 
     1/01/28 – MBIA Insured             
6,300    University of California, Revenue Bonds, Multi-Purpose Projects, Series 2008A,    5/13 at 100.00    Aa1    6,246,545 
     5.000%, 5/15/33 – AMBAC Insured (UB)             
77,910    Total California            78,413,634 
    Colorado – 5.8% (3.6% of Total Investments)             
    Bowles Metropolitan District, Colorado, General Obligation Bonds, Series 2003:             
4,300     5.500%, 12/01/23 – FSA Insured    12/13 at 100.00    AAA    4,596,356 
3,750     5.500%, 12/01/28 – FSA Insured    12/13 at 100.00    AAA    3,895,200 
1,450    Colorado Educational and Cultural Facilities Authority, Charter School Revenue Bonds,    8/14 at 100.00    A    1,439,111 
     Peak-to-Peak Charter School, Series 2004, 5.250%, 8/15/24 – XLCA Insured             
3,750    Colorado Health Facilities Authority, Colorado, Revenue Bonds, Catholic Health Initiatives,    4/18 at 100.00    AAA    3,677,850 
     Series 2006C-1, Trust 1090, 12.515%, 10/01/41 – FSA Insured (IF)             
3,000    E-470 Public Highway Authority, Colorado, Senior Revenue Bonds, Series 2000B, 0.000%,    No Opt. Call    AA    785,700 
     9/01/30 – MBIA Insured             
2,900    E-470 Public Highway Authority, Colorado, Toll Revenue Bonds, Series 2004A, 0.000%, 9/01/34 –    No Opt. Call    AA    579,507 
     MBIA Insured             
19,150    Total Colorado            14,973,724 
    District of Columbia – 0.2% (0.1% of Total Investments)             
665    Washington Convention Center Authority, District of Columbia, Senior Lien Dedicated Tax    10/16 at 100.00    AA    479,957 
     Revenue Bonds, Series 2007, Residuals 1606, 8.249%, 10/01/30 – AMBAC Insured (IF)             
    Florida – 1.3% (0.8% of Total Investments)             
3,000    Pinellas County Health Facilities Authority, Florida, Revenue Bonds, Baycare Health System,    5/13 at 100.00    Aa3 (4)    3,314,490 
     Series 2003, 5.500%, 11/15/27 (Pre-refunded 5/15/13)             
    Georgia – 2.1% (1.3% of Total Investments)             
1,410    DeKalb County, Georgia, Water and Sewer Revenue Bonds, Series 2006A, 5.000%, 10/01/35 –    10/16 at 100.00    AAA    1,429,726 
     FSA Insured             
3,825    Metropolitan Atlanta Rapid Transit Authority, Georgia, Sales Tax Revenue Bonds, Second    1/13 at 100.00    AA+ (4)    4,130,120 
     Indenture Series 2002, 5.000%, 7/01/32 (Pre-refunded 1/01/13) – MBIA Insured             
5,235    Total Georgia            5,559,846 
    Illinois – 3.9% (2.5% of Total Investments)             
905    Cook County School District 100, Berwyn South, Illinois, General Obligation Refunding Bonds,    12/13 at 100.00    Aaa    997,029 
     Series 2003B, 5.250%, 12/01/21 (Pre-refunded 12/01/13) – FSA Insured             
    Cook County School District 145, Arbor Park, Illinois, General Obligation Bonds, Series 2004:             
3,285     5.125%, 12/01/20 – FSA Insured    12/14 at 100.00    Aaa    3,446,852 
2,940     5.125%, 12/01/23 – FSA Insured    12/14 at 100.00    Aaa    3,040,107 
2,500    Illinois Health Facilities Authority, Revenue Bonds, Lake Forest Hospital, Series 2003,    7/13 at 100.00    A–    2,502,550 
     5.250%, 7/01/23             
9,630    Total Illinois            9,986,538 
    Indiana – 10.0% (6.3% of Total Investments)             
2,500    Evansville, Indiana, Sewerage Works Revenue Refunding Bonds, Series 2003A, 5.000%, 7/01/23 -    7/13 at 100.00    AA    2,553,375 
     AMBAC Insured             
2,190    Indiana Bond Bank, Advance Purchase Funding Bonds, Common School Fund, Series 2003B, 5.000%,    8/13 at 100.00    AA    2,238,640 
     8/01/19 – MBIA Insured             
1,860    Indiana Municipal Power Agency, Power Supply Revenue Bonds, Series 2007A, 5.000%, 1/01/42 –    1/17 at 100.00    AA    1,771,576 
     MBIA Insured             
1,000    Indiana University, Student Fee Revenue Bonds, Series 2003O, 5.000%, 8/01/22 – FGIC Insured    8/13 at 100.00    Aa1    1,027,120 
    IPS Multi-School Building Corporation, Indiana, First Mortgage Revenue Bonds, Series 2003:             
11,020     5.000%, 7/15/19 (Pre-refunded 7/15/13) – MBIA Insured    7/13 at 100.00    AA (4)    11,926,946 
6,000     5.000%, 7/15/20 (Pre-refunded 7/15/13) – MBIA Insured    7/13 at 100.00    AA (4)    6,493,800 
24,570    Total Indiana            26,011,457 
    Kansas – 2.5% (1.6% of Total Investments)             
6,250    Kansas Development Finance Authority, Board of Regents, Revenue Bonds, Scientific Research and    4/13 at 102.00    AA    6,511,000 
     Development Facilities Projects, Series 2003C, 5.000%, 10/01/22 – AMBAC Insured             
    Kentucky – 0.4% (0.3% of Total Investments)             
985    Kentucky State Property and Buildings Commission, Revenue Refunding Bonds, Project 77, Series    8/13 at 100.00    AA (4)    1,070,636 
     2003, 5.000%, 8/01/23 (Pre-refunded 8/01/13) – MBIA Insured             
    Louisiana – 2.1% (1.3% of Total Investments)             
5,785    New Orleans, Louisiana, General Obligation Refunding Bonds, Series 2002, 5.300%, 12/01/27 –    12/12 at 100.00    Baa3    5,528,551 
     FGIC Insured             
    Massachusetts – 2.9% (1.8% of Total Investments)             
6,000    Massachusetts Bay Transportation Authority, Senior Sales Tax Revenue Refunding Bonds, Series    7/12 at 100.00    AAA    6,464,340 
     2002A, 5.000%, 7/01/27 (Pre-refunded 7/01/12) – FGIC Insured             
1,125    Massachusetts Development Finance Authority, Revenue Bonds, Middlesex School, Series 2003,    9/13 at 100.00    A1    1,142,798 
     5.125%, 9/01/23             
7,125    Total Massachusetts            7,607,138 
    Michigan – 11.9% (7.4% of Total Investments)             
6,130    Detroit, Michigan, Senior Lien Water Supply System Revenue Bonds, Series 2003A, 5.000%,    7/13 at 100.00    AA (4)    6,658,651 
     7/01/23 (Pre-refunded 7/01/13) – MBIA Insured             
4,465    Detroit, Michigan, Senior Lien Water Supply System Revenue Refunding Bonds, Series 2003C,    7/13 at 100.00    AA    4,482,190 
     5.000%, 7/01/22 – MBIA Insured             
1,000    Michigan State Hospital Finance Authority, Revenue Bonds, Trinity Health Care Group, Series    12/16 at 100.00    AA    978,370 
     2008A, 5.000%, 12/01/31 (UB)             
10,800    Michigan Strategic Fund, Limited Obligation Resource Recovery Revenue Refunding Bonds, Detroit    12/12 at 100.00    Baa1    9,936,972 
     Edison Company, Series 2002D, 5.250%, 12/15/32 – XLCA Insured             
2,250    Romulus Community Schools, Wayne County, Michigan, General Obligation Refunding Bonds, Series    5/11 at 100.00    AA–    2,322,405 
     2001, 5.250%, 5/01/25             
6,500    Wayne County, Michigan, Limited Tax General Obligation Airport Hotel Revenue Bonds, Detroit    12/11 at 101.00    AA    6,396,455 
     Metropolitan Wayne County Airport, Series 2001A, 5.000%, 12/01/30 – MBIA Insured             
31,145    Total Michigan            30,775,043 
    Missouri – 1.2% (0.7% of Total Investments)             
240    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds, Series    3/14 at 100.00    AAA    250,814 
     2004, 5.250%, 3/01/24 – FSA Insured             
215    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds, Series    3/14 at 100.00    AAA    225,154 
     2004, 5.250%, 3/01/23 – FSA Insured             
    Clay County Public School District 53, Liberty, Missouri, General Obligation Bonds,             
    Series 2004:             
1,110     5.250%, 3/01/23 (Pre-refunded 3/01/14) – FSA Insured    3/14 at 100.00    AAA    1,221,599 
1,260     5.250%, 3/01/24 (Pre-refunded 3/01/14) – FSA Insured    3/14 at 100.00    AAA    1,386,680 
2,825    Total Missouri            3,084,247 
    Nebraska – 1.9% (1.2% of Total Investments)             
5,000    Lincoln, Nebraska, Sanitary Sewerage System Revenue Refunding Bonds, Series 2003, 5.000%,    6/13 at 100.00    AA+    5,051,350 
     6/15/28 – MBIA Insured             
    New Mexico – 0.8% (0.5% of Total Investments)             
1,975    New Mexico State University, Revenue Bonds, Series 2004, 5.000%, 4/01/19 – AMBAC Insured    4/14 at 100.00    AA    2,062,433 
    New York – 10.9% (6.8% of Total Investments)             
20    Hudson Yards Infrastructure Corporation, New York, Revenue Bonds, Driver Trust 1649, 2006, 5.121%,    2/17 at 100.00    AA    12,352 
     2/15/47 – MBIA Insured (IF)             
1,960    Hudson Yards Infrastructure Corporation, New York, Revenue Bonds, Series 2006A, 4.500%, 2/15/47 –    2/17 at 100.00    AA    1,710,139 
     MBIA Insured (UB)             
25,000    Metropolitan Transportation Authority, New York, Transportation Revenue Refunding Bonds,    11/12 at 100.00    AA    24,659,500 
     Series 2002F, 5.000%, 11/15/31 – MBIA Insured             
1,850    New York State Urban Development Corporation, Service Contract Revenue Bonds, Series    3/15 at 100.00    AAA    1,900,246 
     2005B, 5.000%, 3/15/25 – FSA Insured (UB)             
28,830    Total New York            28,282,237 
    North Carolina – 3.2% (2.1% of Total Investments)             
8,700    North Carolina Medical Care Commission, Revenue Bonds, Maria Parham Medical Center, Series    10/13 at 100.00    A    8,169,213 
     2003, 5.375%, 10/01/33 – RAAI Insured             
    Ohio – 1.0% (0.6% of Total Investments)             
    Buckeye Tobacco Settlement Financing Authority, Ohio, Tobacco Settlement Asset-Backed Revenue             
    Bonds, Senior Lien, Series 2007A-2:             
70     5.125%, 6/01/24    6/17 at 100.00    BBB    62,408 
710     5.875%, 6/01/30    6/17 at 100.00    BBB    614,122 
685     5.750%, 6/01/34    6/17 at 100.00    BBB    567,084 
1,570     5.875%, 6/01/47    6/17 at 100.00    BBB    1,275,531 
3,035    Total Ohio            2,519,145 
    Oklahoma – 0.4% (0.2% of Total Investments)             
1,000    Oklahoma Capitol Improvement Authority, State Facilities Revenue Bonds, Series 2005F, 5.000%,    7/15 at 100.00    AA    1,014,550 
     7/01/24 – AMBAC Insured             
    Oregon – 3.1% (1.9% of Total Investments)             
8,350    Oregon Health Sciences University, Revenue Bonds, Series 2002A, 5.000%, 7/01/32 – MBIA Insured    1/13 at 100.00    AA    8,067,102 
    Pennsylvania – 7.8% (4.9% of Total Investments)             
3,000    Lehigh County General Purpose Authority, Pennsylvania, Hospital Revenue Bonds, St. Luke’s    8/13 at 100.00    AAA    3,300,660 
     Hospital of Bethlehem, Series 2003, 5.375%, 8/15/33 (Pre-refunded 8/15/13)             
2,000    Philadelphia Gas Works, Pennsylvania, Revenue Bonds, General Ordinance, Fourth Series 1998,    8/13 at 100.00    AAA    1,977,960 
     5.000%, 8/01/32 – FSA Insured (UB)             
925    Philadelphia, Pennsylvania, Water and Wastewater Revenue Bonds, Series 1997A, 5.125%,    8/08 at 101.00    AAA    946,506 
     8/01/27 – AMBAC Insured (ETM)             
13,000    State Public School Building Authority, Pennsylvania, Lease Revenue Bonds, Philadelphia School    6/13 at 100.00    AAA    14,107,600 
     District, Series 2003, 5.000%, 6/01/33 (Pre-refunded 6/01/13) – FSA Insured             
18,925    Total Pennsylvania            20,332,726 
    Puerto Rico – 0.5% (0.3% of Total Investments)             
10,000    Puerto Rico Sales Tax Financing Corporation, Sales Tax Revenue Bonds, Series 2007A, 0.000%,    No Opt. Call    AA    1,347,700 
     8/01/43 – MBIA Insured             
    South Carolina – 7.5% (4.7% of Total Investments)             
5,000    Florence County, South Carolina, Hospital Revenue Bonds, McLeod Regional Medical Center,    11/14 at 100.00    AAA    5,130,750 
     Series 2004A, 5.250%, 11/01/23 – FSA Insured             
    Greenville County School District, South Carolina, Installment Purchase Revenue Bonds,             
    Series 2003:             
3,000     5.000%, 12/01/22 (UB)    12/13 at 100.00    AA    3,041,835 
1,785     5.000%, 12/01/23 (UB)    12/13 at 100.00    AA    1,803,180 
1,365    Myrtle Beach, South Carolina, Water and Sewerage System Revenue Refunding Bonds, Series 2003,    3/13 at 100.00    N/R (4)    1,498,647 
     5.375%, 3/01/19 (Pre-refunded 3/01/13) – FGIC Insured             
8,000    South Carolina Transportation Infrastructure Bank, Revenue Bonds, Series 2002A, 5.000%,    10/12 at 100.00    Aa3    7,875,600 
     10/01/33 – AMBAC Insured             
19,150    Total South Carolina            19,350,012 
    Texas – 11.5% (7.2% of Total Investments)             
7,975    Fort Bend Independent School District, Fort Bend County, Texas, General Obligation Bonds,    8/10 at 100.00    AAA    8,045,499 
     Series 2000, 5.000%, 8/15/25             
12,500    Grand Prairie Independent School District, Dallas County, Texas, General Obligation Bonds,    2/13 at 100.00    AAA    13,562,750 
     Series 2003, 5.125%, 2/15/31 (Pre-refunded 2/15/13) – FSA Insured             
2,000    Houston, Texas, First Lien Combined Utility System Revenue Bonds, Series 2004A, 5.250%,    5/14 at 100.00    AA    2,040,820 
     5/15/25 – MBIA Insured             
5,515    Houston, Texas, General Obligation Refunding Bonds, Series 2002, 5.250%, 3/01/20 – MBIA Insured    3/12 at 100.00    AA    5,723,026 
465    Katy Independent School District, Harris, Fort Bend and Waller Counties, Texas, General    2/12 at 100.00    AAA    484,981 
     Obligation Bonds, Series 2002A, 5.125%, 2/15/18             
28,455    Total Texas            29,857,076 
    Virginia – 0.6% (0.4% of Total Investments)             
1,500    Hampton, Virginia, Revenue Bonds, Convention Center Project, Series 2002, 5.125%, 1/15/28 –    1/13 at 100.00    AA    1,502,625 
     AMBAC Insured             
    Washington – 9.4% (5.9% of Total Investments)             
4,945    Broadway Office Properties, King County, Washington, Lease Revenue Bonds, Washington Project,    12/12 at 100.00    AAA    4,952,269 
     Series 2002, 5.000%, 12/01/31 – MBIA Insured             
5,250    Chelan County Public Utility District 1, Washington, Hydro Consolidated System Revenue Bonds,    7/12 at 100.00    AA    5,263,598 
     Series 2002C, 5.125%, 7/01/33 – AMBAC Insured             
2,135    Kitsap County Consolidated Housing Authority, Washington, Revenue Bonds, Bremerton Government    7/13 at 100.00    A1    2,144,138 
     Center, Series 2003, 5.000%, 7/01/23 – MBIA Insured             
1,935    Pierce County School District 343, Dieringer, Washington, General Obligation Refunding Bonds,    6/13 at 100.00    Aa1    2,062,304 
     Series 2003, 5.250%, 12/01/17 – FGIC Insured             
9,670    Washington State, General Obligation Bonds, Series 2003D, 5.000%, 12/01/21 – MBIA Insured    6/13 at 100.00    AA+    9,949,270 
23,935    Total Washington            24,371,579 
    West Virginia – 1.2% (0.8% of Total Investments)             
3,000    West Virginia State Building Commission, Lease Revenue Refunding Bonds, Regional Jail and    No Opt. Call    AA    3,231,990 
     Corrections Facility, Series 1998A, 5.375%, 7/01/21 – AMBAC Insured             
    Wisconsin – 6.8% (4.3% of Total Investments)             
1,190    Sun Prairie Area School District, Dane County, Wisconsin, General Obligation Bonds, Series    3/14 at 100.00    Aaa    1,299,171 
     2004C, 5.250%, 3/01/24 – FSA Insured             
4,605    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Franciscan Sisters of    9/13 at 100.00    BBB+ (4)    5,166,626 
     Christian Charity Healthcare Ministry, Series 2003A, 5.875%, 9/01/33 (Pre-refunded 9/01/13)             
3,000    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Meriter Hospital Inc.,    No Opt. Call    A1    3,343,950 
     Series 1992A, 6.000%, 12/01/22 – FGIC Insured             
3,600    Wisconsin Health and Educational Facilities Authority, Revenue Bonds, Wheaton Franciscan    8/13 at 100.00    A–    3,062,521 
     Services Inc., Series 2003A, 5.125%, 8/15/33             
4,750    Wisconsin Health and Educational Facilities Authority, Revenue Refunding Bonds, Wausau    8/08 at 102.00    AA    4,844,241 
     Hospital Inc., Series 1998A, 5.125%, 8/15/20 – AMBAC Insured             
17,145    Total Wisconsin            17,716,509 
$       412,105    Total Long-Term Investments (cost $399,072,097) – 155.3%            403,059,703 
    Short-Term Investments – 4.3% (2.7% of Total Investments)             
1,000    Austin, Texas, Water and Wastewater System Revenue Bonds, Tender Option Bond Trust 1281,        A-1    1,000,000 
     Variable Rate Demand Obligations, 2.870%, 5/15/35 – AMBAC Insured (5)             
2,000    Florida Board of Education, Lottery Revenue Bonds, Series 2001B, Trust 570, Variable Rate Demand             
     Obligations, 4.530%, 7/01/14 – FGIC Insured (5)        A-1    2,000,000 
2,300    Lancaster, Pennsylvania, General Obligation Bonds, Tender Option Bond Trust 2007-47, Variable Rate        VMIG-1    2,300,000 
     Demand Obligations, 3.850%, 5/01/15 – AMBAC Insured (5)             
1,200    New Jersey Transportation Trust Fund Authority, Transportation System Bonds, Series 2007, Trust        A-1+    1,200,000 
     2199, Variable Rate Demand Obligations, 2.700%, 6/15/15 – AMBAC Insured (5)             
2,555    New York City, New York, General Obligation Bonds, Variable Rate Demand Obligations, Fiscal        A-1+    2,555,000 
     Series 2001-A6, 2.000%, 11/01/26 – FSA Insured (5)             
2,200    University of North Texas, Financing System Revenue Bonds, Series 2003, Trust 146, Variable Rate             
     Demand Obligations, 2.400%, 3/05/29 (5)        A-1+    2,200,000 
$         11,255    Total Short-Term Investments (cost $11,255,000)            11,255,000 
    Total Investments (cost $410,327,097) – 159.6%            414,314,703 
    Floating Rate Obligations – (7.7)%            (19,995,000)
    Other Assets Less Liabilities – 3.6%            9,309,204 
    Preferred Shares, at Liquidation Value – (55.5)% (6)            (144,000,000)
    Net Assets Applicable to Common Shares – 100%           $  259,628,907 

    As of July 31, 2008, at least 80% of the Fund’s net assets (including net assets attributable to Preferred 
    shares) are invested in municipal securities that are either covered by Original Issue Insurance, Secondary 
    Market Insurance or Portfolio Insurance which ensures the timely payment of principal and interest. Up to 
    20% of the Fund’s net assets (including net assets attributable to Preferred shares) may be invested in 
    municipal securities that are (i) either backed by an escrow or trust containing sufficient U.S. Government 
    or U.S. Government agency securities (also ensuring the timely payment of principal and interest), or (ii) 
    rated, at the time of investment, within the four highest grades (Baa or BBB or better by Moody’s, Standard 
    & Poor’s or Fitch) or unrated but judged to be of comparable quality by the Adviser. 
(1)    All percentages shown in the Portfolio of Investments are based on net assets applicable to Common 
    shares unless otherwise noted. 
(2)    Optional Call Provisions: Dates (month and year) and prices of the earliest optional call or redemption. 
    There may be other call provisions at varying prices at later dates. Certain mortgage-backed securities 
    may be subject to periodic principal paydowns. 
(3)    Ratings: Using the higher of Standard & Poor’s Group (“Standard & Poor’s”) or Moody’s Investor Service, 
    Inc. (“Moody’s”) rating. Ratings below BBB by Standard & Poor’s or Baa by Moody’s are considered to be 
    below investment grade. 
    The Portfolio of Investments may reflect the ratings on certain bonds insured by ACA, AMBAC, CIFG, FGIC, 
    MBIA, RAAI and XLCA as of July 31, 2008. Subsequent to July 31, 2008, and during the period this 
    Portfolio of Investments was prepared, there may have been reductions to the ratings of certain bonds 
    resulting from changes to the ratings of the underlying insurers both during the period and after the period 
    end. Such reductions would likely reduce the effective rating of many of the bonds insured by that insurer 
    or insurers presented at period end. 
(4)    Backed by an escrow or trust containing sufficient U.S. Government or U.S. Government agency securities 
    which ensure the timely payment of principal and interest. Such investments are normally considered to 
    be equivalent to AAA rated securities. 
(5)    Investment has a maturity of more than one year, but has variable rate and demand features which qualify 
    it as a short-term investment. The rate disclosed is that in effect at the end of the reporting period. This 
    rate changes periodically based on market conditions or a specified market index. 
(6)    Preferred Shares, at Liquidation Value as a percentage of total investments is (34.8)%. 
N/R    Not rated. 
(ETM)    Escrowed to maturity. 
(IF)    Inverse floating rate investment. 
(UB)    Underlying bond of an inverse floating rate trust reflected as a financing transaction pursuant to the 
    provisions of SFAS No. 140. 

Income Tax Information

The following information is presented on an income tax basis. Differences between amounts for financial statement and federal income tax purposes are primarily due to timing differences in recognizing taxable market discount, timing differences in recognizing certain gains and losses on investment transactions and the treatment of investments in inverse floating rate transactions subject to SFAS No. 140. To the extent that differences arise that are permanent in nature, such amounts are reclassified within the capital accounts on the Statement of Assets and Liabilities presented in the annual report, based on their federal tax basis treatment; temporary differences do not require reclassification. Temporary and permanent differences do not impact the net asset value of the Fund.

At July 31, 2008, the cost of investments was $390,267,637.
Gross unrealized appreciation and gross unrealized depreciation of investments at July 31, 2008,
were as follows:

Gross unrealized:     
 Appreciation    $11,365,956 
 Depreciation    (7,318,994)
Net unrealized appreciation (depreciation) of investments    $  4,046,962 

Item 2. Controls and Procedures.

  1. The registrant's principal executive and principal financial officers, or persons performing similar functions, have concluded that the registrant's disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940, as amended (the "1940 Act") (17 CFR 270.30a-3(c))) are effective, as of a date within 90 days of the filing date of this report that includes the disclosure required by this paragraph, based on their evaluation of the controls and procedures required by Rule 30a-3(b) under the 1940 Act (17 CFR 270.30a-3(b)) and Rule 13a-15(b) or 15d-15(b) under the Securities Exchange Act of 1934 (17 CFR 240.13a-15(b) or 240.15d-15(b)).
  2. There were no changes in the registrant's internal control over financial reporting (as defined in Rule 30a-3(d) under the 1940 Act (17 CFR 270.30a-3(d)) that occurred during the registrant's last fiscal quarter that have materially affected, or are reasonably likely to materially affect, the registrant's internal control over financial reporting.

Item 3. Exhibits.

File as exhibits as part of this Form a separate certification for each principal executive officer and principal financial officer of the registrant as required by Rule 30a-2(a) under the 1940 Act (17 CFR 270.30a-2(a)), exactly as set forth below: See EX-99 CERT attached hereto.


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

(Registrant)         Nuveen Insured Tax-Free Advantage Municipal Fund         

By (Signature and Title)          /s/ Kevin J. McCarthy                    
                                                  Kevin J. McCarthy
                                                  Vice President and Secretary

Date         September 29, 2008        

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By (Signature and Title)         /s/ Gifford R. Zimmerman                    
                                                 Gifford R. Zimmerman
                                                 Chief Administrative Officer (principal executive officer) 

Date         September 29, 2008        

By (Signature and Title)         /s/ Stephen D. Foy                              
                                                 Stephen D. Foy
                                                 Vice President and Controller (principal financial officer) 

Date        September 29, 2008