Filed by Sanofi-Synthelabo Pursuant to Rule 135 and Rule 425(a) under the United States Securities Act of 1933, as amended, and deemed filed pursuant to Rule 14d-2(b)(2) of the United States Securities Exchange Act of 1934, as amended Subject Company: Aventis Commission File No. 001-10378 Date: January 28, 2004 ON JANUARY 28, 2004, THE FOLLOWING ADVERTISEMENT WAS PUBLISHED ON BEHALF OF SANOFI-SYNTHELABO IN THE FINANCIAL TIMES EUROPEAN EDITION. * * * * WE REFUSE TO ACCEPT THAT THERE ISN'T A FASTER WAY TO FIND A MEDICINE FOR TOMMY'S DISEASE. [Image of child in hospital bed] Who is going to tell Tommy that the medicine that could cure him won't be ready for 20 years? You? No. No one. Joining forces with Aventis will represent a giant step forward for research. We will be able to provide patients with new drugs and innovative solutions faster. Together, we will harness our complementary skills to create a leading pharmaceutical group (No.1 in Europe and No.3 worldwide) committed to improving healthcare and capable of driving strong, sustainable and profitable growth. SANOFI-SYNTHELABO'S OFFER TO AVENTIS'S SHAREHOLDERS BECAUSE HEALTH MATTERS This advertisement does not constitute an offer to sell or an offer to purchase any securities www.sanofi-synthelabo.com