At what cost? Debate rages over cholesterol drugs By: CNBC.com News August 06, 2015 at 12:13 PM EDT Estimates of annual spending on PCSK9 drugs have been as high as $150 billion, but drugmakers expect it to be much lower. Read More >> Related Stocks: Amgen Express Scripts Holding Regeneron Pharmaceuticals Sanofi-Aventis S.A. ADR